UCSF’s innovative, collaborative approach to patient care, research and education spans disciplines across the life sciences, making it a world leader in scientific discovery and its translation to improving health.
Dr. Abuabara studies the impact of inflammatory skin disease on overall health and the role of the skin in the aging process. Her interdisciplinary scientific approach combines genomic, physiological, environmental, and psychosocial variables to understand patient outcomes over time. Her goal is to develop truly personalized interventions that address both the pathophysiological and sociocultural aspects of disease to improve the lives of patients.
Diana Alba is an Assistant Professor of Medicine in the Division of Endocrinology at the University of California, San Francisco. As a physician-scientist, her research program is focused on identifying the transcriptional pathways that regulate adipose tissue function during normal development and obesity. Her work investigates how adipose tissue dysfunction, particularly through fibrotic remodeling, drives insulin resistance and metabolic dysfunction.
Rheumatoid arthritis (RA) afflicts millions globally, causing significant joint deformity, pain, and functional disability. RA is without cure and its cause is unknown, but CD4 T cells—immune cells widely accepted to play a key role in RA pathogenesis—from patients with RA become activated by proteins through their T cell receptor (called “antigen-specific T cells”) and cause arthritis. Dr. Ashouri’s research uses a unique tool to identify and characterize these antigen-activated T cells in both a mouse model of RA and human RA.
The goal of the lab is to understand how development of hematopoietic stem cells (HSCs), their clonal composition and competition, and their progeny affect initiation of clonal blood disorders. Clonal blood disorders, including malignant diseases such as myelodysplastic syndromes (MDS) and acute myeloid leukemia, are states of significant disturbance of the balanced clonal output.
Dr. Muriel Babey is an Assistant Professor of Medicine at UCSF. She is board-certified by the American Board of Internal Medicine in the subspecialty of Endocrinology, Diabetes, and Metabolism. As a physician-scientist in the Ingraham lab, she engages in cutting-edge research at the interface of skeletal health, metabolism, and aging. She is interested in how other tissues, such as the brain, affect bone health, especially during aging or in poor metabolic health.
Dr. Carnevale is a physician-scientist who treats patients with gastrointestinal cancers, and also performs research into finding novel therapies for these diseases.
I'm a pediatric immunologist and rheumatologist dedicated to improving our understanding of immune regulation to advance care for patients with immune system disorders. My clinical practice is focused on diagnosing and managing patients with complex or unknown immune system disorders. My research area is focused on studying genes that regulate the immune system. We utilize CRISPR/Cas9 to generate mouse models harboring human mutations to help elucidate the molecular mechanism driving disease.
