UCSF’s innovative, collaborative approach to patient care, research and education spans disciplines across the life sciences, making it a world leader in scientific discovery and its translation to improving health.

Infection and immunity

Eukaryotic cell uptake of heparin-coated microspheres: a model of host cell invasion by Chlamydia trachomatis.

Infection and immunity

Stephens RS, Fawaz FS, Kennedy KA, Koshiyama K, Nichols B, van Ooij C, Engel JN

Pseudomonas aeruginosa induces type-III-secretion-mediated apoptosis of macrophages and epithelial cells.

Infection and immunity

Hauser AR, Engel JN

Pili binding to asialo-GM1 on epithelial cells can mediate cytotoxicity or bacterial internalization by Pseudomonas aeruginosa.

Infection and immunity

Comolli JC, Waite LL, Mostov KE, Engel JN

Pseudomonas aeruginosa gene products PilT and PilU are required for cytotoxicity in vitro and virulence in a mouse model of acute pneumonia.

Infection and immunity

Comolli JC, Hauser AR, Waite L, Whitchurch CB, Mattick JS, Engel JN

Pili binding to asialo-GM1 on epithelial cells can mediate cytotoxicity or bacterial internalization by Pseudomonas aeruginosa.

Infection and immunity

Comolli JC, Waite LL, Mostov KE, Engel JN

Fusion of Chlamydia trachomatis-containing inclusions is inhibited at low temperatures and requires bacterial protein synthesis.

Infection and immunity

Van Ooij C, Homola E, Kincaid E, Engel J

Fusion of Chlamydia trachomatis-containing inclusions is inhibited at low temperatures and requires bacterial protein synthesis.

Infection and immunity

Van Ooij C, Homola E, Kincaid E, Engel J

Enhanced protective antibody responses to PspA after intranasal or subcutaneous injections of PspA genetically fused to granulocyte-macrophage colony-stimulating factor or interleukin-2.

Infection and immunity

Wortham C, Grinberg L, Kaslow DC, Briles DE, McDaniel LS, Lees A, Flora M, Snapper CM, Mond JJ

Defects in type III secretion correlate with internalization of Pseudomonas aeruginosa by epithelial cells.

Infection and immunity

Hauser AR, Fleiszig S, Kang PJ, Mostov K, Engel JN

Defects in type III secretion correlate with internalization of Pseudomonas aeruginosa by epithelial cells.

Infection and immunity

Hauser AR, Fleiszig S, Kang PJ, Mostov K, Engel JN

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