The Journal of Immunology

Innate type 2 immunity controls hair follicle commensalism by Demodex mites.

The Journal of Immunology

Roberto R Ricardo-Gonzalez, Maya E Kotas, Claire O’Leary, Iliana Tenvooren, Diana Marquez, Katelyn Singh, William Damsky, Chang Liao, Andrew Schroeder, Jarish Cohen, Marlys S Fassett, Jinwoo Lee, Scott G Daniel, Kyle Bittinger, Roberto Efrain Diaz, James Fraser, Karl Mark Ansel, Matthew Spitzer, Hong-Erh Liang, Richard M Locksley

HIV-specific CD8 T cells from elite controllers have an epigenetic imprint that preserves effector functions.

The Journal of Immunology

Adolfo B Frias, Rachel L Rutishauser, Ashish Arunkumar Sharma, Tian Mi, Hossam Aly Abdelsamed, Caitlin Zebley, Christian M Constantz, Mars Stone, Michael Busch, Steven Deeks, Rafick Sekaly, Ben A Youngblood

Colitis alters the antigen-specific response to skin commensal bacteria and predisposes to neutrophilic skin inflammation.

The Journal of Immunology

Geil Ramvielle Merana, Miqdad Dhariwala, Laura Dwyer, Tiffany Scharschmidt

MAIT cells are imprinted by the microbiota in early life and promote tissue repair.

The Journal of Immunology

Michael G Constantinides, Verena M. Link, Samira Tamoutounour, Andrea C. Wong, P. Juliana Perez-Chaparro, Seong-Ji Han, Y. Erin Chen, Kelin Li, Sepideh Farhat, Antonin Weckel, Siddharth R. Krishnamurthy, Ivan Vujkovic-Cvijin, Jonathan L. Linehan, Nicolas Bouladoux, E. Dean Merrill, Sobhan Roy, Daniel J. Cua, Erin J. Adams, Avinash Bhandoola, Tiffany C. Scharschmidt, Jeffrey Aubé, Michael A. Fischbach, Yasmine Belkaid

Sphingosine 1-phosphate lyase promotes the type I interferon-mediated innate immune response to influenza but is subjected to degradation by influenza A virus NS1.

The Journal of Immunology

Jennifer J Wolf, Chuan Xia, Madhuvanthi Vijayan, Yuleum Song, Caleb J Studstill, Hanh Ngo, Marc C Johnson, Julie D Saba, Stephen Alexander, Bumsuk Hahm

Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function.

The Journal of Immunology

Eric Shifrut, Julia Carnevale, Alan Ashworth, Alexander Marson

IL-15 drives CD8 T cell cycling and differentiation in chronic HIV-1 infection (VIR6P.1162).

The Journal of Immunology

souheil younes, carey shive, Arnold Reynaldi, Michael Freeman, Soumya Panigrahi, Jacob Estes, Jodi Anderson, Timothy Schacker, Miles Davenport, Joseph McCune, Peter Hunt, Sulggi Lee, Sergio Serrano-Villar, David Canaday, Cheryl Cameron, Rafick-Pierre Sekaly, Benigno Rodriguez, Scott Sieg, Michael Lederman

Cellular and molecular mechanisms for lupus nephritis in a mouse model of systemic lupus erythematosus (159.4).

The Journal of Immunology

Si-Han Hai, Viola Lam, Brian Cook, Michelle Hermiston

Impact of TLR9 on hyper-responsive ITAM signaling in a mouse model of SLE (47.24).

The Journal of Immunology

Robyn Mills, Viola Lam, Diana Tobler, Nir Oksenberg, Nicole Cresalia, Mark Anderson, Jian-Hua Mao, Arthur Weiss, Michelle Hermiston

An activating mutation in CD45 generates a novel murine model of hemophagocytic disorders in the context of a MHC Class 1 restricted TCR. (109.11).

The Journal of Immunology

Rachelle Tibbetts, Viola Lam, Nicole Cresalia, Fleur DeGraaf, Nira Goren, Lawrence Wong, Si-Han Hai, Robyn Mills, Alfonso Roque, Weiss Arthur, Michelle Hermiston