Blood

Prothrombotic Antibodies Targeting the Spike Protein's Receptor-Binding Domain in Severe COVID-19.

Blood

Zhu W, Zheng Y, Yu M, Witman N, Zhou L, Wei J, Zhang Y, Topchyan P, Nguyen C, Janecke R, Padmanabhan A, Baumann Kreuziger L, White GC, Hari P, Gu T, Fields AT, Kornblith L, Aster RH, Zhu J, Cui W, Jobe SM, Graham MB, Wang D, Wang D, Wen R

Preclinical Activity of RAS(ON) Multi-Selective Inhibitor RMC-7977 and Therapeutic Combinations in AML with Signaling Mutations.

Blood

Bogdan Popescu, Madison Piao, Sydney Abelson, Carolina E. Morales, Khadija Yousuf, Jose M. Rivera, Cheryl A C Peretz, Elliot Stieglitz, Catherine C. Smith

CDK8 Inhibition Represses Monocyte-like Gene Expression in Acute Myeloid Leukemia Cells and Antagonizes In Vivo Resistance to FLT3 Inhibition.

Blood

Timothy T. Ferng, Samantha M. Pintar, Vanessa E. Kennedy, Shaheen Kabir, Theodore C. Tarver, Veronica Steri, Paul Phojanakong, Juwita Hübner, Carolina E. Morales, Jose M. Rivera, Aaron C. Logan, Benjamin Braun, Elliot Stieglitz, Luke A. Gilbert, Catherine C. Smith

AML Derived Induced Pluripotent Stem Cells Reveal a Genotype-Independent Effect of Monocytic Differentiation in Mediating Venetoclax Resistance.

Blood

Matthew F Jones, Cheryl A C Peretz, Vanessa E. Kennedy, Elaine Tran, Andrew Koh, Andriana Kotini, Malgorzata Olszewska, Eirini Papapetrou, Catherine C. Smith

Trial in Progress: Update on the TACL T2020-003 Randomized Phase 2 Trial to Improve Diet and Exercise in Acute Lymphoblastic Leukemia (IDEAL-2).

Blood

Etan Orgel, Sarah K. Tasian, Yueh-Yun Chi, Jemily Malvar, Christina M. Dieli-Conwright, Rubi Buxton, Mackenzie Frederick, Hannah Williams, Karen R Rabin, Susan R Rheingold, Robin Norris, Tamara P. Miller, Brent L. Wood, Ellynore Florendo, Ellen Chang, Lisa Hartman, Mallorie M. Heneghan, Michelle L. Hermiston, Joel Kaplan, Tamra Slone, Deepa Bhojwani, Alan S. Wayne, Steven D. Mittelman

Retrospective Cohort Analysis of Response and Survival of Children, Adolescents, and Young Adults (CAYA) with Relapsed and/or Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Lymphoma (T-LL) Treated with Curative Intent: A TACL Consortium

Blood

Melinda G Pauly, Yueh-Yun Chi, Jemily Malvar, Roy Leong, Susan Colace, Nathan Gossai, Nobuko Hijiya, Chintan Parekh, Susan R Rheingold, Anupam Verma, Bill H Chang, Todd M Cooper, Andrew Doan, Yamilet Huerta, Kelly Elizabeth Faulk, Diane Hanna, Kenneth Matthew Heym, Mallorie M. Heneghan, Joel Kaplan, Luciano Dalla-Pozza, Seth E. Karol, Andrew E. Place, Jenna Rossoff, Eric S. Schafer, Tamra Slone, Michelle L. Hermiston, Maria Luisa Sulis

Immunoglobulin Sequencing Biologically Distinguishes B-Lymphoblastic Lymphoma from Acute Lymphoblastic Leukemia and Reveals a Spectrum of Disease Dissemination across Clinical Stages.

Blood

Carol Fries Simpson, Lik Wee Lee, Hongyue Wang, Diana G. Adlowitz, Philip Rock, Brent L. Wood, Rachel E. Rau, Kara L. Davis, Anne Angiolillo, Meenakshi Devidas, David T. Teachey, Karen R Rabin, Birte Wistinghausen, Donald Barkauskas, Robert J. Hayashi, Richard Burack, Carl E Allen, Michelle L. Hermiston, Ilan R. Kirsch

A Phase 1 Clinical Trial of NKTR-255 with CD19-22 CAR-T Cell Therapy for Refractory B-cell Acute Lymphoblastic Leukemia.

Blood

Srinagesh HK, Jackson C, Shiraz P, Jeyakumar N, Hamilton MP, Egeler E, Mavroukakis S, Kuo A, Cancilla J, Sahaf B, Agarwal N, Kanegai AM, Kramer AM, Arai S, Bharadwaj S, Dahiya S, Hosoya H, Johnston LJ, Kennedy VE, Liedtke M, Lowsky R, Mikkilineni L, Negrin RS, Rezvani AR, Sidana S, Shizuru JA, Smith M, Weng WK, Feldman SA, Frank MJ, Lee Z, Tagliaferri M, Marcondes AMQ, Miklos DB, Mackall CL, Muffly L

MRD at the End of Induction and EFS in T-cell Lymphoblastic Lymphoma: Children's Oncology Group Trial AALL1231.

Blood

Hayashi RJ, Hermiston ML, Wood BL, Teachey DT, Devidas M, Chen Z, Annett RD, Asselin BL, August K, Cho S, Dunsmore KP, Freedman JL, Galardy PJ, Harker-Murray P, Horton TM, Jaju A, Lam A, Messinger YH, Miles RR, Okada M, Patel S, Schafer ES, Schechter T, Shimano KA, Singh N, Steele A, Sulis ML, Vargas S, Winter SS, Wood C, Zweider-McKay PA, Loh ML, Hunger SP, Raetz EA, Bollard CM, Allen CE

Old is gold: frontline etoposide for pHLH.

Blood

Gulati N, Hermiston ML

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