Sarah Puryear, MD, MPH


I am an infectious disease (ID) physician and clinical researcher whose work focuses on the intersection of alcohol, HIV, and tuberculosis in sub-Saharan Africa. I am currently an assistant professor in the Division of HIV, ID, and Global Medicine at the University of California, San Francisco (UCSF). I am trained in infectious diseases, HIV and TB prevention and epidemiology, and work as a physician in the Ward 86 HIV clinic and the inpatient Internal Medicine and HIV/ID consult services at San Francisco General Hospital. I have worked in research and public health programming in sub-Saharan Africa since 2007.

My research focuses on defining HIV care outcomes and TB epidemiology among persons who engage in alcohol use, who are a high-risk group for poor outcomes and may benefit from novel service interventions. Currently, I am focused on understanding the epidemiology of alcohol use and its relationship to HIV care outcomes among youth living with HIV in sub-Saharan Africa with the ultimate goal of developing youth-specific, culturally appropriate alcohol interventions. Additionally, I am co-leading a randomized controlled trial within the SEARCH-Sapphire study (PIs: Havlir, Petersen, Kamya) to test a novel recruitment and intervention strategy to improve viral suppression among people living with HIV who have hazardous levels of alcohol use. Across my research, I am interested in leveraging alcohol biomarkers to better understand the measurement of alcohol use.


Effect of a brief alcohol counselling intervention on HIV viral suppression and alcohol use among persons with HIV and unhealthy alcohol use in Uganda and Kenya: a randomized controlled trial.

Journal of the International AIDS Society

Puryear SB, Mwangwa F, Opel F, Chamie G, Balzer LB, Kabami J, Ayieko J, Owaraganise A, Kakande E, Agengo G, Bukusi E, Kabageni S, Omoding D, Bacon M, Schrom J, Woolf-King S, Petersen ML, Havlir DV, Kamya M, Hahn JA

Universal HIV Testing and Treatment with Patient-Centered Care Improves ART Uptake and Viral Suppression among Adults Reporting Hazardous Alcohol Use in Uganda and Kenya.

Journal of acquired immune deficiency syndromes (1999)

Puryear SB, Ayieko J, Hahn JA, Mucunguzi A, Owaraganise A, Schwab J, Balzer LB, Kwarisiima D, Charlebois ED, Cohen CR, Bukusi EA, Petersen ML, Havlir DV, Kamya MR, Chamie G

Efficacy of alcohol reduction interventions among people with HIV as evaluated by self-report and a phosphatidylethanol (PEth) outcome: protocol for a systematic review and individual participant data meta-analysis.

BMJ open

Kane JC, Allen I, Fatch R, Scheffler A, Emenyonu N, Puryear SB, Chirayil P, So-Armah K, Kahler CW, Magidson JF, Conroy AA, Edelman EJ, Woolf-King S, Parry C, Kiene SM, Chamie G, Adong J, Go VF, Cook RL, Muyindike W, Morojele N, Blokhina E, Krupitsky E, Fiellin DA, Hahn JA

Effects of a COVID-19 Public Health Lockdown on Drinking and Health Behavior Among Persons with HIV and with Unhealthy Alcohol use in Uganda.

AIDS and behavior

Beesiga B, Marson K, Fatch R, Emenyonu NI, Adong J, Kekibiina A, Puryear S, Lodi S, McDonell MG, Muyindike WR, Kamya MR, Hahn JA, Chamie G

Associations between alcohol and cigarette use and type 1 and 2 myocardial infarction among people with HIV.

HIV medicine

Drumright LN, Nance RM, Ruderman SA, Ma J, Whitney BM, Hahn A, Fredericksen RJ, Luu B, Lober WB, Moore RD, Budoff MJ, Keruly JC, Christopoulos K, Puryear S, Willig A, Cropsey K, Mathews WC, Cachay E, Bamford L, Eron JJ, Napravnik S, Mayer KH, O'Cleirigh C, Mccaul ME, Chander G, Feinstein MJ, Saag MS, Kitahata MM, Heckbert SR, Crane HM, Delaney JAC

ID Learning Unit: Understanding Advances in the Treatment of Latent Tuberculosis Infection among People with HIV

Open forum infectious diseases

Nicky J Mehtani, Sarah Puryear, Paul Pham, Kelly E Dooley, Maunank Shah

Higher Levels of Alcohol Use Are Associated With Latent Tuberculosis Infection in Adults Living With Human Immunodeficiency Virus.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Puryear SB, Fatch R, Beesiga B, Kekibiina A, Lodi S, Marson K, Emenyonu NI, Muyindike WR, Kwarisiima D, Hahn JA, Chamie G

Associations between alcohol use and HIV care cascade outcomes among adults undergoing population-based HIV testing in East Africa.

AIDS (London, England)

Puryear SB, Balzer LB, Ayieko J, Kwarisiima D, Hahn JA, Charlebois ED, Clark TD, Cohen CR, Bukusi EA, Kamya MR, Petersen ML, Havlir DV, Chamie G

Disseminated Cutaneous and Osteoarticular Sporotrichosis Mimicking Pyoderma Gangrenosum.

Open forum infectious diseases

Saeed L, Weber RJ, Puryear SB, Bahrani E, Peluso MJ, Babik JM, Haemel A, Coates SJ

HIV seroconversion among Baltimore City residents tested at a mobile van programme.

Sexually transmitted infections

Puryear S, Burnett P, Page KR, Muvva R, Chaulk P, Ghanem KG, Monroe A

High magnitude of under nutrition among HIV infected adults who have not started ART in Tanzania--a call to include nutrition care and treatment in the test and treat model

BMC Nutrition

Bruno F. Sunguya, Nzovu K. Ulenga, Hellen Siril, Sarah Puryear, Eric Aris, Expeditho Mtisi, Edith Tarimo, David P. Urassa, Wafaie Fawzi & Ferdnand Mugusi

Yield of contact tracing from pediatric tuberculosis index cases in Gaborone, Botswana.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

Puryear S, Seropola G, Ho-Foster A, Arscott-Mills T, Mazhani L, Firth J, Goldfarb DM, Ncube R, Bisson GP, Steenhoff AP