Minnie Sarwal, MD, PhD

Professor
Surgery
--

Professor in Residence, Surgery, Division of MultiOrgan Transplantation, UCSF
Professor, Medicine, Pediatrics, UCSF
Medical Director (interim), Kidney-Pancreas Transplant Program, UCSF
Director, Precision Transplant Medicine, SarwalLab, UCSF
Co-Director, T32 Training Grant, Transplant Surgery, UCSF
Capstone Mentor, Masters in Translational Medicine, Berkeley/UCSF
Consulting Professor, Haas, University of California, Berkeley
Professor, Immunology, Peds, Surgery (1997-2012), Stanford University
Medical Director (2008-2012), Pediatric Kidney Transplant Program, Stanford University

Summary:
Minnie Sarwal has over 30 years of clinical experience and 25 years of research experience in translational immunogenetics, genomics, proteomics and informatics. She holds a PhD in Molecular Genetics from Cambridge University (Christ's College), under the mentorship of Nobel Laureate Sydney Brenner; a Diploma in Child Health from London, UK; Membership of the Royal College of Physicians and elected Fellow of the Royal College of Physicians, UK.

Dr. Sarwal has held the Professor of Surgery/Immunology/Peds and the Medical Director position in the Peds Kidney Transplant Program at Stanford University. She headed a personalized medicine initiative for Sutter Health and is currently Professor of Surgery at UCSF. In an international election, she was selected Councillor for the TTS in 2014, and in a university wide election voted in as Senator-at-large on the Faculty Senate for Stanford Medical School. She has been an Asian-American and Women's Mentor at Stanford University, has chaired sections for the AST/ASTS/TTS, and serves on NIH study sections.

Minnie has directed the Sarwal Lab since 1997 and manages high caliber clinical and scientific staff. She founded Organ-I, a company for personalization of transplant medicine, spun out of Stanford; recently acquired by Immucor.

Minnie has leadership skills in the development, delivery and evaluation of services in large medical centers in the USA and England, securing pharma and NIH funding and expanding clinical services in a competitive environment. She is a KOL in the field of renal and transplant medicine, genomics, proteomics and immunology. As PI for industry and NIH multicenter clinical trials, she leads trial design, execution, and human subject safety policies. As an enterpreneur, she has founded and sold a diagnostic company and is experienced in legal, fiscal, regulatory and reimbursement requirements for product development and commercialization.

Publications: 

The Banff 2022 Kidney Meeting Work Plan: Data-driven Refinement of the Banff Classification for Renal Allografts.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Roufosse C, Naesens M, Haas M, Lefaucheur C, Mannon RB, Afrouzian M, Alachkar N, Aubert O, Bagnasco SM, Batal I, Bellamy COC, Broecker V, Budde K, Clahsen-Van Groningen M, Coley SM, Cornell LD, Dadhania D, Demetris AJ, Einecke G, Farris AB, Fogo AB, Friedewald J, Gibson IW, Horsfield C, Huang E, Husain SA, Jackson AM, Kers J, Kikic Ž, Klein A, Kozakowski N, Liapis H, Mangiola M, Montgomery RA, Nankinvell B, Neil DAH, Nickerson P, Rabant M, Randhawa P, Riella LV, Rosales I, Royal V, Sapir-Pichhadze R, Sarder P, Sarwal M, Schinstock C, Stegall M, Solez K, van der Laak J, Wiebe C, Colvin RB, Loupy A, Mengel M

Proteome Analysis for Inflammation Related to Acute and Convalescent Infection.

Inflammation

Sigdel TK, Sur S, Boada P, McDermott SM, Arlehamn CSL, Murray KO, Bockenstedt LK, Kerwin M, Reed EF, Harris E, Stuart K, Peters B, Sesma A, Montgomery RR, Sarwal MM

Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection.

Nature communications

Lamarthée B, Callemeyn J, Van Herck Y, Antoranz A, Anglicheau D, Boada P, Becker JU, Debyser T, De Smet F, De Vusser K, Eloudzeri M, Franken A, Gwinner W, Koshy P, Kuypers D, Lambrechts D, Marquet P, Mathias V, Rabant M, Sarwal MM, Senev A, Sigdel TK, Sprangers B, Thaunat O, Tinel C, Van Brussel T, Van Craenenbroeck A, Van Loon E, Vaulet T, Bosisio F, Naesens M

Plasma proteome perturbation for CMV DNAemia in kidney transplantation.

PloS one

Sigdel TK, Boada P, Kerwin M, Rashmi P, Gjertson D, Rossetti M, Sur S, Munar D, Cimino J, Ahn R, Pickering H, Sen S, Parmar R, Fatou B, Steen H, Schaenman J, Bunnapradist S, Reed EF, Sarwal MM, CMV Systems Immunobiology Group

Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors.

Annals of translational medicine

Rashmi P, Sigdel TK, Rychkov D, Damm I, Da Silva AA, Vincenti F, Lourenco AL, Craik CS, Reiser J, Sarwal MM

Longitudinal serum proteomics analyses identify unique and overlapping host response pathways in Lyme disease and West Nile virus infection.

Frontiers in immunology

Boada P, Fatou B, Belperron AA, Sigdel TK, Smolen KK, Wurie Z, Levy O, Ronca SE, Murray KO, Liberto JM, Rashmi P, Kerwin M, Montgomery RR, Bockenstedt LK, Steen H, Sarwal MM

Perturbations of the T-cell immune repertoire in kidney transplant rejection.

Frontiers in immunology

Sigdel TK, Fields PA, Liberto J, Damm I, Kerwin M, Hood J, Towfighi P, Sirota M, Robins HS, Sarwal MM

Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination.

Nature immunology

Fourati S, Tomalin LE, Mul? MP, Chawla DG, Gerritsen B, Rychkov D, Henrich E, Miller HER, Hagan T, Diray-Arce J, Dunn P, Human Immunology Project Consortium (HIPC), Levy O, Gottardo R, Sarwal MM, Tsang JS, Su?rez-Fari?as M, Pulendran B, Kleinstein SH, S?kaly RP

The Immune Signatures data resource, a compendium of systems vaccinology datasets.

Scientific data

Diray-Arce J, Miller HER, Henrich E, Gerritsen B, Mul? MP, Fourati S, Gygi J, Hagan T, Tomalin L, Rychkov D, Kazmin D, Chawla DG, Meng H, Dunn P, Campbell J, Human Immunology Project Consortium (HIPC), Sarwal M, Tsang JS, Levy O, Pulendran B, Sekaly R, Floratos A, Gottardo R, Kleinstein SH, Su?rez-Fari?as M

Malnutrition and immune cell subsets in children undergoing kidney transplantation.

Pediatric transplantation

Shaw BI, Lee HJ, Ettenger R, Grimm P, Reed EF, Sarwal M, Stempora L, Warshaw B, Zhao C, Martinez OM, MacIver NJ, Kirk AD, Chambers ET

A reference tissue atlas for the human kidney.

Science advances

Hansen J, Sealfon R, Menon R, Eadon MT, Lake BB, Steck B, Anjani K, Parikh S, Sigdel TK, Zhang G, Velickovic D, Barwinska D, Alexandrov T, Dobi D, Rashmi P, Otto EA, Rivera M, Rose MP, Anderton CR, Shapiro JP, Pamreddy A, Winfree S, Xiong Y, He Y, de Boer IH, Hodgin JB, Barisoni L, Naik AS, Sharma K, Sarwal MM, Zhang K, Himmelfarb J, Rovin B, El-Achkar TM, Laszik Z, He JC, Dagher PC, Valerius MT, Jain S, Satlin LM, Troyanskaya OG, Kretzler M, Iyengar R, Azeloglu EU, Kidney Precision Medicine Project

Mass cytometry reveals single-cell kinetics of cytotoxic lymphocyte evolution in CMV-infected renal transplant patients.

Proceedings of the National Academy of Sciences of the United States of America

Ishiyama K, Arakawa-Hoyt J, Aguilar OA, Damm I, Towfighi P, Sigdel T, Tamaki S, Babdor J, Spitzer MH, Reed EF, Sarwal MM, Lanier LL, CMV Systems Immunobiology Group

Through the Looking Glass: Unraveling the Stage-Shift of Acute Rejection in Renal Allografts.

Journal of clinical medicine

Sarwal RD, Yazar W, Titzler N, Wong J, Lai CH, Chin C, Krieger D, Stoll J, Dias Lourenco F, Sarwal MM, Ghosh S

Urinary Biomarkers for Kidney Allograft Injury.

Transplantation

Jin PH, Sarwal RD, Sarwal MM

Multiplexed droplet single-cell sequencing (Mux-Seq) of normal and transplant kidney.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Rashmi P, Sur S, Sigdel TK, Boada P, Schroeder AW, Damm I, Kretzler M, Hodgin J, Sarwal MM, Kidney Precision Medicine Project

FcER1: A Novel Molecule Implicated in the Progression of Human Diabetic Kidney Disease.

Frontiers in immunology

Sur S, Nguyen M, Boada P, Sigdel TK, Sollinger H, Sarwal MM

Improving Clinical Trials for Anticomplement Therapies in Complement-Mediated Glomerulopathies: Report of a Scientific Workshop Sponsored by the National Kidney Foundation.

American journal of kidney diseases : the official journal of the National Kidney Foundation

Bomback AS, Appel GB, Gipson DS, Hladunewich MA, Lafayette R, Nester CM, Parikh SV, Smith RJH, Trachtman H, Heeger PS, Ram S, Rovin BH, Ali S, Arceneaux N, Ashoor I, Bailey-Wickins L, Barratt J, Beck L, Cattran DC, Cravedi P, Erkan E, Fervenza F, Frazer-Abel AA, Fremeaux-Bacchi V, Fuller L, Gbadegesin R, Hogan JJ, Kiryluk K, le Quintrec-Donnette M, Licht C, Mahan JD, Pickering MC, Quigg R, Rheault M, Ronco P, Sarwal MM, Sethna C, Spino C, Stegall M, Vivarelli M, Feldman DL, Thurman JM

The Importance of Bringing Transplantation Tolerance to the Clinic.

Transplantation

Cosimi AB, Ascher NL, Emond JC, Kaufman DB, Madsen JC, Miller J, Monaco AP, Montgomery RA, Newell KA, Sánchez-Fueyo A, Sarwal MM, Scandling JD, Strober S, Todo S, Weir MR, Sachs DH

A Comprehensive Urine Proteome Database Generated From Patients With Various Renal Conditions and Prostate Cancer.

Frontiers in medicine

Swensen AC, He J, Fang AC, Ye Y, Nicora CD, Shi T, Liu AY, Sigdel TK, Sarwal MM, Qian WJ

Rationale and design of the Kidney Precision Medicine Project.

Kidney international

de Boer IH, Alpers CE, Azeloglu EU, Balis UGJ, Barasch JM, Barisoni L, Blank KN, Bomback AS, Brown K, Dagher PC, Dighe AL, Eadon MT, El-Achkar TM, Gaut JP, Hacohen N, He Y, Hodgin JB, Jain S, Kellum JA, Kiryluk K, Knight R, Laszik ZG, Lienczewski C, Mariani LH, McClelland RL, Menez S, Moledina DG, Mooney SD, O'Toole JF, Palevsky PM, Parikh CR, Poggio ED, Rosas SE, Rosengart MR, Sarwal MM, Schaub JA, Sedor JR, Sharma K, Steck B, Toto RD, Troyanskaya OG, Tuttle KR, Vazquez MA, Waikar SS, Williams K, Wilson FP, Zhang K, Iyengar R, Kretzler M, Himmelfarb J, Kidney Precision Medicine Project

Use of the Tissue Common Rejection Module Score in Kidney Transplant as an Objective Measure of Allograft Inflammation.

Frontiers in immunology

Zarinsefat A, Guerra JMA, Sigdel T, Damm I, Sarwal R, Chan-On C, Szabo G, Aguilar-Frasco JL, Ixtlapale-Carmona X, Salinas-Ramos C, Ramirez-Martinez L, Ramirez C, Vilatoba M, Morales Buenrostro LE, Alberu JM, Sarwal MM

Corrigendum: Near-Single-Cell Proteomics Profiling of the Proximal Tubular and Glomerulus of the Normal Human Kidney.

Frontiers in medicine

Sigdel TK, Piehowski PD, Roy S, Liberto J, Hansen JR, Swensen AC, Zhao R, Zhu Y, Rashmi P, Schroeder A, Damm I, Sur S, Luo J, Yang Y, Qian WJ, Sarwal MM

Single-Cell RNA Sequencing of Tocilizumab-Treated Peripheral Blood Mononuclear Cells as an in vitro Model of Inflammation.

Frontiers in genetics

Zarinsefat A, Hartoularos G, Rychkov D, Rashmi P, Chandran S, Vincenti F, Yee CJ, Sarwal MM

Molecular Diversity of Clinically Stable Human Kidney Allografts.

JAMA network open

Rychkov D, Sur S, Sirota M, Sarwal MM

A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project.

Physiological genomics

El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, Parikh S, Zhang G, Dobi D, Dunn KW, Otto EA, Anderton CR, Carson JM, Luo J, Park C, Hamidi H, Zhou J, Hoover P, Schroeder A, Joanes M, Azeloglu EU, Sealfon R, Winfree S, Steck B, He Y, D'Agati V, Iyengar R, Troyanskaya OG, Barisoni L, Gaut J, Zhang K, Laszik Z, Rovin BH, Dagher PC, Sharma K, Sarwal MM, Hodgin JB, Alpers CE, Kretzler M, Jain S

Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro model of inflammation.

bioRxiv : the preprint server for biology

Zarinsefat A, Hartoularos G, Chandran S, Yee CJ, Vincenti F, Sarwal MM

Impact of Sarcopenia on Simultaneous Pancreas and Kidney Transplantation Outcomes: A Retrospective Observational Cohort Study.

Transplantation direct

Meier RPH, Noguchi H, Kelly YM, Sarwal M, Conti G, Ward C, Halleluyan R, Tavakol M, Stock PG, Freise CE

Near-Single-Cell Proteomics Profiling of the Proximal Tubular and Glomerulus of the Normal Human Kidney.

Frontiers in medicine

Sigdel TK, Piehowski PD, Roy S, Liberto J, Hansen JR, Swensen AC, Zhao R, Zhu Y, Rashmi P, Schroeder A, Damm I, Sur S, Luo J, Yang Y, Qian WJ, Sarwal MM, Kidney Precision Medicine Project (KPMP) Consortium

Relationship between antithymocyte globulin, T cell phenotypes, and clinical outcomes in pediatric kidney transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Shaw BI, Lee HJ, Chan C, Ettenger R, Grimm P, Pearl M, Reed EF, Robien MA, Sarwal M, Stempora L, Warshaw B, Zhao C, Martinez OM, Kirk AD, Chambers ET

Peripheral Blood RNA Sequencing Unravels a Differential Signature of Coding and Noncoding Genes by Types of Kidney Allograft Rejection.

Kidney international reports

Pineda S, Sur S, Sigdel T, Nguyen M, Crespo E, Torija A, Meneghini M, Gomà M, Sirota M, Bestard O, Sarwal MM

Clinical and Analytical Validation of a Novel Urine-Based Test for the Detection of Allograft Rejection in Renal Transplant Patients.

Journal of clinical medicine

Nolan N, Valdivieso K, Mani R, Yang JYC, Sarwal RD, Katzenbach P, Chalasani K, Hongo D, Lugtu G, Mark C, Chen E, Nijor R, Savoca D, Wexler DS, Whitson T, Huang SJ, Lu LH, Zawada RJX, Hytopoulos E, Sarwal MM

Targeted Urine Metabolomics for Monitoring Renal Allograft Injury and Immunosuppression in Pediatric Patients.

Journal of clinical medicine

Sigdel TK, Schroeder AW, Yang JYC, Sarwal RD, Liberto JM, Sarwal MM

Avoidance of CNI and steroids using belatacept-Results of the Clinical Trials in Organ Transplantation 16 trial.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Mannon RB, Armstrong B, Stock PG, Mehta AK, Farris AB, Watson N, Morrison Y, Sarwal M, Sigdel T, Bridges N, Robien M, Newell KA, Larsen CP

A urine score for noninvasive accurate diagnosis and prediction of kidney transplant rejection.

Science translational medicine

Yang JYC, Sarwal RD, Sigdel TK, Damm I, Rosenbaum B, Liberto JM, Chan-On C, Arreola-Guerra JM, Alberu J, Vincenti F, Sarwal MM

Use of biomarkers to improve immunosuppressive drug development and outcomes in renal organ transplantation: A meeting report.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Mannon RB, Morris RE, Abecassis M, Axelrod D, Bala S, Friedman GS, Heeger PS, Lentine KL, Loupy A, Murphy B, Nickerson P, Sarwal M, O'Doherty I, Spear N, Karpen SR

Long-term follow-up of beta cell replacement therapy in 10 HIV-infected patients with renal failure secondary to type 1 diabetes mellitus.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Roll GR, Posselt AM, Freise J, Baird J, Syed S, Mo Kang S, Hirose R, Szot GL, Zarinsefat A, Feng S, Worner G, Sarwal M, Stock PG

Non-radiological assessment of kidney stones using the kidney injury test (KIT), a spot urine assay.

BJU international

Yang JYC, Sarwal RD, Ky K, Dong V, Stoller M, Sarwal MM, Chi T

Further Evidence That the Soluble Urokinase Plasminogen Activator Receptor Does Not Directly Injure Mice or Human Podocytes.

Transplantation

Harel E, Shoji J, Abraham V, Miller L, Laszik ZG, King A, Dobi D, Szabo G, Hann B, Sarwal MM, Craik CS, Vincenti F

Noninvasive Urinary Monitoring of Progression in IgA Nephropathy.

International journal of molecular sciences

Yang JYC, Sarwal RD, Fervenza FC, Sarwal MM, Lafayette RA

A urinary Common Rejection Module (uCRM) score for non-invasive kidney transplant monitoring.

PloS one

Sigdel TK, Yang JYC, Bestard O, Schroeder A, Hsieh SC, Liberto JM, Damm I, Geraedts ACM, Sarwal MM

A Modified Injector and Sample Acquisition Protocol Can Improve Data Quality and Reduce Inter-Instrument Variability of the Helios Mass Cytometer.

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Lee BH, Kelly G, Bradford S, Davila M, Guo XV, Amir ED, Thrash EM, Solga MD, Lannigan J, Sellers B, Candia J, Tsang J, Montgomery RR, Tamaki SJ, Sigdel TK, Sarwal MM, Lanier LL, Tian Y, Kim C, Hinz D, Peters B, Sette A, Rahman AH

Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing.

Nature communications

Pineda S, Sigdel TK, Liberto JM, Vincenti F, Sirota M, Sarwal MM

A Novel Multi-Biomarker Assay for Non-Invasive Quantitative Monitoring of Kidney Injury.

Journal of clinical medicine

Watson D, Yang JYC, Sarwal RD, Sigdel TK, Liberto JM, Damm I, Louie V, Sigdel S, Livingstone D, Soh K, Chakraborty A, Liang M, Lin PC, Sarwal MM

Assessment of Postdonation Outcomes in US Living Kidney Donors Using Publicly Available Data Sets.

JAMA network open

Chen J, Bhattacharya S, Sirota M, Laiudompitak S, Schaefer H, Thomson E, Wiser J, Sarwal MM, Butte AJ

Call for an End to Unethical Transplant Practices: A Concerted Effort by the Transplant Community.

Transplantation

Haberal M, Cantarovich M, Muller E, Fung JJ, Sarwal M, Tullius SG, Ascher N

Cell-Free DNA and CXCL10 Derived from Bronchoalveolar Lavage Predict Lung Transplant Survival.

Journal of clinical medicine

Yang JYC, Verleden SE, Zarinsefat A, Vanaudenaerde BM, Vos R, Verleden GM, Sarwal RD, Sigdel TK, Liberto JM, Damm I, Watson D, Sarwal MM

Optimizing Detection of Kidney Transplant Injury by Assessment of Donor-Derived Cell-Free DNA via Massively Multiplex PCR.

Journal of clinical medicine

Sigdel TK, Archila FA, Constantin T, Prins SA, Liberto J, Damm I, Towfighi P, Navarro S, Kirkizlar E, Demko ZP, Ryan A, Sigurjonsson S, Sarwal RD, Hseish SC, Chan-On C, Zimmermann B, Billings PR, Moshkevich S, Sarwal MM

The common rejection module in chronic rejection post lung transplantation.

PloS one

Sacreas A, Yang JYC, Vanaudenaerde BM, Sigdel TK, Liberto JM, Damm I, Verleden GM, Vos R, Verleden SE, Sarwal MM

Urinary Virome Perturbations in Kidney Transplantation.

Frontiers in medicine

Sigdel TK, Mercer N, Nandoe S, Nicora CD, Burnum-Johnson K, Qian WJ, Sarwal MM

Mechanisms and biomarkers of immune quiescence in kidney transplantation.

Human immunology

Chan-On C, Liberto JM, Sarwal MM

Targeted Transcriptional Profiling of Kidney Transplant Biopsies.

Kidney international reports

Sigdel TK, Nguyen M, Dobi D, Hsieh SC, Liberto JM, Vincenti F, Sarwal MM, Laszik Z

LC-SRM-Based Targeted Quantification of Urinary Protein Biomarkers.

Methods in molecular biology (Clifton, N.J.)

Gao Y, Wang H, Nicora CD, Shi T, Smith RD, Sigdel TK, Sarwal MM, Camp DG, Qian WJ

Optimization for Peptide Sample Preparation for Urine Peptidomics.

Methods in molecular biology (Clifton, N.J.)

Sigdel TK, Nicora CD, Qian WJ, Sarwal MM

Protein biomarkers in renal transplantation.

Expert review of proteomics

Chakraborty A, Sarwal M

Expression of Mitochondrial-Encoded Genes in Blood Differentiate Acute Renal Allograft Rejection.

Frontiers in medicine

Roedder S, Sigdel T, Hsieh SC, Cheeseman J, Metes D, Macedo C, Reed EF, Gritsch HA, Zeevi A, Shapiro R, Kirk AD, Sarwal MM

Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Chandran S, Tang Q, Sarwal M, Laszik ZG, Putnam AL, Lee K, Leung J, Nguyen V, Sigdel T, Tavares EC, Yang JYC, Hellerstein M, Fitch M, Bluestone JA, Vincenti F

Molecular and Functional Noninvasive Immune Monitoring in the ESCAPE Study for Prediction of Subclinical Renal Allograft Rejection.

Transplantation

Crespo E, Roedder S, Sigdel T, Hsieh SC, Luque S, Cruzado JM, Tran TQ, Grinyó JM, Sarwal MM, Bestard O

Transplant genetics and genomics.

Nature reviews. Genetics

Yang JY, Sarwal MM

Relationship Among Viremia/Viral Infection, Alloimmunity, and Nutritional Parameters in the First Year After Pediatric Kidney Transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Ettenger R, Chin H, Kesler K, Bridges N, Grimm P, Reed EF, Sarwal M, Sibley R, Tsai E, Warshaw B, Kirk AD

A combined biomarker and clinical panel for chronic graft versus host disease diagnosis.

The journal of pathology. Clinical research

Pidala J, Sigdel TK, Wang A, Hsieh S, Inamoto Y, Martin PJ, Flowers ME, Hansen JA, Lee SJ, Sarwal MM

Unraveling the Role of Allo-Antibodies and Transplant Injury.

Frontiers in immunology

Matsuda Y, Sarwal MM

Advances in diagnostics for transplant rejection.

Expert review of molecular diagnostics

Nasr M, Sigdel T, Sarwal M

Intragraft Antiviral-Specific Gene Expression as a Distinctive Transcriptional Signature for Studies in Polyomavirus-Associated Nephropathy.

Transplantation

Sigdel TK, Bestard O, Salomonis N, Hsieh SC, Torras J, Naesens M, Tran TQ, Roedder S, Sarwal MM

Self-antigens and rejection: a proteomic analysis.

Current opinion in organ transplantation

Yang JY, Sigdel TK, Sarwal MM

Mining the human urine proteome for monitoring renal transplant injury.

Kidney international

Sigdel TK, Gao Y, He J, Wang A, Nicora CD, Fillmore TL, Shi T, Webb-Robertson BJ, Smith RD, Qian WJ, Salvatierra O, Camp DG, Sarwal MM

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Autophagy

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, et al

Non-HLA Antibodies in Clinical Transplantation.

Clinical transplants

Chan-On C, Sarwal M

Circulating CD40 autoantibody and suPAR synergy drives glomerular injury.

Annals of translational medicine

Wei C, Sigdel TK, Sarwal MM, Reiser J

A Computational Gene Expression Score for Predicting Immune Injury in Renal Allografts.

PloS one

Sigdel TK, Bestard O, Tran TQ, Hsieh SC, Roedder S, Damm I, Vincenti F, Sarwal MM

Computational Models for Transplant Biomarker Discovery.

Frontiers in immunology

Wang A, Sarwal MM

Transcriptional Perturbations in Graft Rejection.

Transplantation

Vitalone MJ, Sigdel TK, Salomonis N, Sarwal RD, Hsieh SC, Sarwal MM

Pediatric Deceased Donation-A Report of the Transplantation Society Meeting in Geneva.

Transplantation

Martin DE, Nakagawa TA, Siebelink MJ, Bramstedt KA, Brierley J, Dobbels F, Rodrigue JR, Sarwal M, Shapiro R, Dominguez-Gil B, Danovitch G, Sweet SC, Trompeter RS, Moazam F, Bos MA, Delmonico FL, Transplantation Society

Tolerance associated gene expression following allogeneic hematopoietic cell transplantation.

PloS one

Pidala J, Bloom GC, Eschrich S, Sarwal M, Enkemann S, Betts BC, Beato F, Yoder S, Anasetti C

Perturbations in the urinary exosome in transplant rejection.

Frontiers in medicine

Sigdel TK, Ng YW, Lee S, Nicora CD, Qian WJ, Smith RD, Camp DG, Sarwal MM

Mapping novel immunogenic epitopes in IgA nephropathy.

Clinical journal of the American Society of Nephrology : CJASN

Woo SH, Sigdel TK, Dinh VT, Vu MT, Sarwal MM, Lafayette RA

A Three-Gene Assay for Monitoring Immune Quiescence in Kidney Transplantation.

Journal of the American Society of Nephrology : JASN

Roedder S, Li L, Alonso MN, Hsieh SC, Vu MT, Dai H, Sigdel TK, Bostock I, Macedo C, Metes D, Zeevi A, Shapiro R, Salvatierra O, Scandling J, Alberu J, Engleman E, Sarwal MM

The kSORT assay to detect renal transplant patients at high risk for acute rejection: results of the multicenter AART study.

PLoS medicine

Roedder S, Sigdel T, Salomonis N, Hsieh S, Dai H, Bestard O, Metes D, Zeevi A, Zeevi A, Gritsch A, Cheeseman J, Macedo C, Peddy R, Medeiros M, Vincenti F, Asher N, Salvatierra O, Shapiro R, Kirk A, Reed EF, Reed E, Sarwal MM

Endothelial cell antibodies associated with novel targets and increased rejection.

Journal of the American Society of Nephrology : JASN

Jackson AM, Sigdel TK, Delville M, Hsieh SC, Dai H, Bagnasco S, Montgomery RA, Sarwal MM

A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation.

Science translational medicine

Delville M, Sigdel TK, Wei C, Li J, Hsieh SC, Fornoni A, Burke GW, Bruneval P, Naesens M, Jackson A, Alachkar N, Canaud G, Legendre C, Anglicheau D, Reiser J, Sarwal MM

Inhibition of intracellular clusterin attenuates cell death in nephropathic cystinosis.

Journal of the American Society of Nephrology : JASN

Sansanwal P, Li L, Sarwal MM

Transcriptional profiling of belatacept and calcineurin inhibitor therapy in renal allograft recipients.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Vitalone MJ, Ganguly B, Hsieh S, Latek R, Kulbokas EJ, Townsend R, Sarwal MM

Quality of life is improved and kidney function preserved in patients with nephropathic cystinosis treated for 2 years with delayed-release cysteamine bitartrate.

The Journal of pediatrics

Langman CB, Greenbaum LA, Grimm P, Sarwal M, Niaudet P, Deschenes G, Cornelissen EA, Morin D, Cochat P, Elenberg E, Hanna C, Gaillard S, Bagger MJ, Rioux P

Optimization for peptide sample preparation for urine peptidomics.

Clinical proteomics

Sigdel TK, Nicora CD, Hsieh SC, Dai H, Qian WJ, Camp DG, Sarwal MM

Identification of common blood gene signatures for the diagnosis of renal and cardiac acute allograft rejection.

PloS one

Li L, Khush K, Hsieh SC, Ying L, Luikart H, Sigdel T, Roedder S, Yang A, Valantine H, Sarwal MM

The identification of novel potential injury mechanisms and candidate biomarkers in renal allograft rejection by quantitative proteomics.

Molecular & cellular proteomics : MCP

Sigdel TK, Salomonis N, Nicora CD, Ryu S, He J, Dinh V, Orton DJ, Moore RJ, Hsieh SC, Dai H, Thien-Vu M, Xiao W, Smith RD, Qian WJ, Camp DG, Sarwal MM

A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation.

The Journal of experimental medicine

Khatri P, Roedder S, Kimura N, De Vusser K, Morgan AA, Gong Y, Fischbein MP, Robbins RC, Naesens M, Butte AJ, Sarwal MM

Quality of life after organ transplantation in children.

Current opinion in organ transplantation

Sarwal MM, Bagga A

Biologic markers of chronic GVHD.

Bone marrow transplantation

Pidala J, Sarwal M, Roedder S, Lee SJ

A rapid noninvasive assay for the detection of renal transplant injury.

Transplantation

Sigdel TK, Vitalone MJ, Tran TQ, Dai H, Hsieh SC, Salvatierra O, Sarwal MM

Multicenter evaluation of a standardized protocol for noninvasive gene expression profiling.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Keslar KS, Lin M, Zmijewska AA, Sigdel TK, Tran TQ, Ma L, Bhasin M, Rao P, Ding R, Iklé DN, Mannon RB, Sarwal MM, Strom TB, Reed EF, Heeger PS, Suthanthiran M, Fairchild RL

Identification of gene microarray expression profiles in patients with chronic graft-versus-host disease following allogeneic hematopoietic cell transplantation.

Clinical immunology (Orlando, Fla.)

Kohrt HE, Tian L, Li L, Alizadeh AA, Hsieh S, Tibshirani RJ, Strober S, Sarwal M, Lowsky R

Immune response profiling identifies autoantibodies specific to Moyamoya patients.

Orphanet journal of rare diseases

Sigdel TK, Shoemaker LD, Chen R, Li L, Butte AJ, Sarwal MM, Steinberg GK

The clinical impact of humoral immunity in pediatric renal transplantation.

Journal of the American Society of Nephrology : JASN

Chaudhuri A, Ozawa M, Everly MJ, Ettenger R, Dharnidharka V, Benfield M, Mathias R, Portale A, McDonald R, Harmon W, Kershaw D, Vehaskari VM, Kamil E, Baluarte HJ, Warady B, Li L, Sigdel TK, Hsieh SC, Dai H, Naesens M, Waskerwitz J, Salvatierra O, Terasaki PI, Sarwal MM

Discovery and customized validation of antibody targets by protein arrays and indirect ELISA.

Methods in molecular biology (Clifton, N.J.)

Sigdel TK, Sarwal MM

The pits and pearls in translating operational tolerance biomarkers into clinical practice.

Current opinion in organ transplantation

Roedder S, Gao X, Sarwal MM

A peripheral blood diagnostic test for acute rejection in renal transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Li L, Khatri P, Sigdel TK, Tran T, Ying L, Vitalone MJ, Chen A, Hsieh S, Dai H, Zhang M, Naesens M, Zarkhin V, Sansanwal P, Chen R, Mindrinos M, Xiao W, Benfield M, Ettenger RB, Dharnidharka V, Mathias R, Portale A, McDonald R, Harmon W, Kershaw D, Vehaskari VM, Kamil E, Baluarte HJ, Warady B, Davis R, Butte AJ, Salvatierra O, Sarwal MM

p62/SQSTM1 prominently accumulates in renal proximal tubules in nephropathic cystinosis.

Pediatric nephrology (Berlin, Germany)

Sansanwal P, Sarwal MM

Complete steroid avoidance is effective and safe in children with renal transplants: a multicenter randomized trial with three-year follow-up.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Sarwal MM, Ettenger RB, Dharnidharka V, Benfield M, Mathias R, Portale A, McDonald R, Harmon W, Kershaw D, Vehaskari VM, Kamil E, Baluarte HJ, Warady B, Tang L, Liu J, Li L, Naesens M, Sigdel T, Waskerwitz J, Salvatierra O

Subclinical inflammation and chronic renal allograft injury in a randomized trial on steroid avoidance in pediatric kidney transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Naesens M, Salvatierra O, Benfield M, Ettenger RB, Dharnidharka V, Harmon W, Mathias R, Sarwal MM, SNS01-NIH-CCTPT Multicenter Trial

Protein and peptide biomarkers in organ transplantation.

Biomarkers in medicine

Sigdel TK, Gao X, Sarwal MM

A randomized controlled crossover trial with delayed-release cysteamine bitartrate in nephropathic cystinosis: effectiveness on white blood cell cystine levels and comparison of safety.

Clinical journal of the American Society of Nephrology : CJASN

Langman CB, Greenbaum LA, Sarwal M, Grimm P, Niaudet P, Deschênes G, Cornelissen E, Morin D, Cochat P, Matossian D, Gaillard S, Bagger MJ, Rioux P

Guidelines for the use and interpretation of assays for monitoring autophagy.

Autophagy

Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, et al

Tolerance and withdrawal of immunosuppressive drugs in patients given kidney and hematopoietic cell transplants.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Scandling JD, Busque S, Dejbakhsh-Jones S, Benike C, Sarwal M, Millan MT, Shizuru JA, Lowsky R, Engleman EG, Strober S

A common peripheral blood gene set for diagnosis of operational tolerance in pediatric and adult liver transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Li L, Wozniak LJ, Rodder S, Heish S, Talisetti A, Wang Q, Esquivel C, Cox K, Chen R, McDiarmid SV, Sarwal MM

Non-HLA antibodies to immunogenic epitopes predict the evolution of chronic renal allograft injury.

Journal of the American Society of Nephrology : JASN

Sigdel TK, Li L, Tran TQ, Khatri P, Naesens M, Sansanwal P, Dai H, Hsieh SC, Sarwal MM

Cell-free DNA as a measure of transplant injury.

Clinical transplants

Sigdel TK, Sarwal MM

Profiling of autoantibodies in IgA nephropathy, an integrative antibiomics approach.

Clinical journal of the American Society of Nephrology : CJASN

Sigdel TK, Woo SH, Dai H, Khatri P, Li L, Myers B, Sarwal MM, Lafayette RA

Functional proteogenomics--embracing complexity.

Seminars in immunology

Sarwal MM, Sigdel TK, Salomon DR

Progressive histological damage in renal allografts is associated with expression of innate and adaptive immunity genes.

Kidney international

Naesens M, Khatri P, Li L, Sigdel TK, Vitalone MJ, Chen R, Butte AJ, Salvatierra O, Sarwal MM

Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease.

Science translational medicine

Dudley JT, Sirota M, Shenoy M, Pai RK, Roedder S, Chiang AP, Morgan AA, Sarwal MM, Pasricha PJ, Butte AJ

Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis.

Nature medicine

Wei C, El Hindi S, Li J, Fornoni A, Goes N, Sageshima J, Maiguel D, Karumanchi SA, Yap HK, Saleem M, Zhang Q, Nikolic B, Chaudhuri A, Daftarian P, Salido E, Torres A, Salifu M, Sarwal MM, Schaefer F, Morath C, Schwenger V, Zeier M, Gupta V, Roth D, Rastaldi MP, Burke G, Ruiz P, Reiser J

Soluble human leukocyte antigen-G in pediatric renal transplantation.

Transplantation

Zarkhin V, Bezchinsky M, Li L, Sarwal MM

Applications of translational bioinformatics in transplantation.

Clinical pharmacology and therapeutics

Khatri P, Sarwal MM, Butte AJ

Rituximab treatment for recurrence of nephrotic syndrome in a pediatric patient after renal transplantation for congenital nephrotic syndrome of Finnish type.

Pediatric transplantation

Chaudhuri A, Kambham N, Sutherland S, Grimm P, Alexander S, Concepcion W, Sarwal M, Wong C

Profiling the proteome in renal transplantation.

Proteomics. Clinical applications

Sigdel TK, Lee S, Sarwal MM

Transplantomics and biomarkers in organ transplantation: a report from the first international conference.

Transplantation

Sarwal MM, Benjamin J, Butte AJ, Davis MM, Wood K, Chapman J

Organ transplantation after cardiac death.

Lancet (London, England)

Naesens M, Sarwal MM, Kuypers DR

Efficacy and safety of thymoglobulin induction as an alternative approach for steroid-free maintenance immunosuppression in pediatric renal transplantation.

Transplantation

Li L, Chaudhuri A, Chen A, Zhao X, Bezchinsky M, Concepcion W, Salvatierra O, Sarwal MM

Protein microarrays discover angiotensinogen and PRKRIP1 as novel targets for autoantibodies in chronic renal disease.

Molecular & cellular proteomics : MCP

Butte AJ, Sigdel TK, Wadia PP, Miklos DB, Sarwal MM

Analysis of clinical variables associated with tolerance in pediatric liver transplant recipients.

Pediatric transplantation

Talisetti A, Hurwitz M, Sarwal M, Berquist W, Castillo R, Bass D, Concepcion W, Esquivel CO, Cox K

Expression of soluble HLA-G identifies favorable outcomes in liver transplant recipients.

Transplantation

Zarkhin V, Talisetti A, Li L, Wozniak LJ, McDiarmid SV, Cox K, Esquivel C, Sarwal MM

Insights into novel cellular injury mechanisms by gene expression profiling in nephropathic cystinosis.

Journal of inherited metabolic disease

Sansanwal P, Li L, Hsieh SC, Sarwal MM

Differentially expressed RNA from public microarray data identifies serum protein biomarkers for cross-organ transplant rejection and other conditions.

PLoS computational biology

Chen R, Sigdel TK, Li L, Kambham N, Dudley JT, Hsieh SC, Klassen RB, Chen A, Caohuu T, Morgan AA, Valantine HA, Khush KK, Sarwal MM, Butte AJ

Molecular diagnostics in transplantation.

Nature reviews. Nephrology

Naesens M, Sarwal MM

Steroid minimization for sirolimus-treated renal transplant recipients.

Clinical transplantation

Matas AJ, Granger D, Kaufman DB, Sarwal MM, Ferguson RM, Woodle ES, Gill JS

Pediatric kidney transplantation.

Pediatric clinics of North America

Shapiro R, Sarwal MM

Pediatric renal transplantation: an overview and update.

Current opinion in pediatrics

Gulati A, Sarwal MM

Cell type-specific gene expression differences in complex tissues.

Nature methods

Shen-Orr SS, Tibshirani R, Khatri P, Bodian DL, Staedtler F, Perry NM, Hastie T, Sarwal MM, Davis MM, Butte AJ

Compartmental localization and clinical relevance of MICA antibodies after renal transplantation.

Transplantation

Li L, Chen A, Chaudhuri A, Kambham N, Sigdel T, Chen R, Sarwal MM

Integrative urinary peptidomics in renal transplantation identifies biomarkers for acute rejection.

Journal of the American Society of Nephrology : JASN

Ling XB, Sigdel TK, Lau K, Ying L, Lau I, Schilling J, Sarwal MM

The yin and yang of B cells in graft rejection and tolerance.

Transplantation reviews (Orlando, Fla.)

Zarkhin V, Chalasani G, Sarwal MM

Caspase-4 may play a role in loss of proximal tubules and renal injury in nephropathic cystinosis.

Pediatric nephrology (Berlin, Germany)

Sansanwal P, Kambham N, Sarwal MM

Shotgun proteomics identifies proteins specific for acute renal transplant rejection.

Proteomics. Clinical applications

Sigdel TK, Kaushal A, Gritsenko M, Norbeck AD, Qian WJ, Xiao W, Camp DG, Smith RD, Sarwal MM

Mitochondrial autophagy promotes cellular injury in nephropathic cystinosis.

Journal of the American Society of Nephrology : JASN

Sansanwal P, Yen B, Gahl WA, Ma Y, Ying L, Wong LJ, Sarwal MM

Balancing efficacy and toxicity of kidney transplant immunosuppression.

Transplantation proceedings

Naesens M, Lerut E, Sarwal M, Van Damme B, Vanrenterghem Y, Kuypers DR

Deconvoluting the 'omics' for organ transplantation.

Current opinion in organ transplantation

Sarwal MM

Promotion of altruistic donation.

Transplantation

Tilney N, Murray J, Thistlethwaite R, Norman D, Delmonico F, Hanto D, Leichtman A, Danovitch G, Sayegh M, Shapiro R, Harmon W, Salvatierra O, Brennan D, McDiarmid S, Stock P, Pomfret L, Bennett W, Conti D, Metzger B, Sarwal M, Cosimi AB

Long-term outcome following pediatric liver transplantation for metabolic disorders.

Pediatric transplantation

Stevenson T, Millan MT, Wayman K, Berquist WE, Sarwal M, Johnston EE, Esquivel CO, Enns GM

C3 polymorphisms and outcomes of renal allografts.

The New England journal of medicine

Naesens M, Butte AJ, Sarwal MM

Expression of complement components differs between kidney allografts from living and deceased donors.

Journal of the American Society of Nephrology : JASN

Naesens M, Li L, Ying L, Sansanwal P, Sigdel TK, Hsieh SC, Kambham N, Lerut E, Salvatierra O, Butte AJ, Sarwal MM

Steroid-free immunosuppression since 1999: 129 pediatric renal transplants with sustained graft and patient benefits.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Li L, Chang A, Naesens M, Kambham N, Waskerwitz J, Martin J, Wong C, Alexander S, Grimm P, Concepcion W, Salvatierra O, Sarwal MM

Standardizing resistive indices in healthy pediatric transplant recipients of adult-sized kidneys.

Pediatric transplantation

Gholami S, Sarwal MM, Naesens M, Ringertz HG, Barth RA, Balise RR, Salvatierra O

Identifying compartment-specific non-HLA targets after renal transplantation by integrating transcriptome and "antibodyome" measures.

Proceedings of the National Academy of Sciences of the United States of America

Li L, Wadia P, Chen R, Kambham N, Naesens M, Sigdel TK, Miklos DB, Sarwal MM, Butte AJ

Calcineurin inhibitor nephrotoxicity.

Clinical journal of the American Society of Nephrology : CJASN

Naesens M, Kuypers DR, Sarwal M

Using gene arrays in diagnosis of rejection.

Current opinion in organ transplantation

Khatri P, Sarwal MM

Interpreting the proteome and peptidome in transplantation.

Advances in clinical chemistry

Sigdel TK, Klassen RB, Sarwal MM

Combined liver-kidney transplantation in children: indications and outcome.

Pediatric transplantation

Sutherland SM, Alexander SR, Sarwal MM, Berquist WE, Concepcion W

A critical look at the immunologically favorable adult-sized kidney transplant in small children.

Pediatric transplantation

Salvatierra O, Concepcion W, Sarwal M

Out with the old, in with the new: immunosuppression minimization in children.

Current opinion in organ transplantation

Sarwal MM

A randomized, prospective trial of rituximab for acute rejection in pediatric renal transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Zarkhin V, Li L, Kambham N, Sigdel T, Salvatierra O, Sarwal MM

Microarrays: monitoring for transplant tolerance and mechanistic insights.

Clinics in laboratory medicine

Zarkhin V, Sarwal MM

The proteogenomic path towards biomarker discovery.

Pediatric transplantation

Sigdel TK, Sarwal MM

Renal transplantation in children with thrombosis of the inferior vena cava requires careful assessment and planning.

Pediatric nephrology (Berlin, Germany)

Salvatierra O, Concepcion W, Sarwal MM

Patient selection critical for calcineurin inhibitor withdrawal in pediatric kidney transplantation.

Pediatric transplantation

Weintraub L, Li L, Kambham N, Alexander S, Concepcion W, Miller K, Wong C, Salvatierra O, Sarwal M

"To B or not to B?" B-cells and graft rejection.

Transplantation

Zarkhin V, Li L, Sarwal M

In praise of arrays.

Pediatric nephrology (Berlin, Germany)

Ying L, Sarwal M

Characterization of intra-graft B cells during renal allograft rejection.

Kidney international

Zarkhin V, Kambham N, Li L, Kwok S, Hsieh SC, Salvatierra O, Sarwal MM

Optimizing protein recovery for urinary proteomics, a tool to monitor renal transplantation.

Clinical transplantation

Sigdel TK, Lau K, Schilling J, Sarwal M

Maturation of dose-corrected tacrolimus predose trough levels in pediatric kidney allograft recipients.

Transplantation

Naesens M, Salvatierra O, Li L, Kambham N, Concepcion W, Sarwal M

Liposomal amphotericin B associated with severe hyperphosphatemia.

The Pediatric infectious disease journal

Sutherland SM, Hong DK, Balagtas J, Gutierrez K, Dvorak CC, Sarwal M

Potential influence of tacrolimus and steroid avoidance on early graft function in pediatric renal transplantation.

Pediatric transplantation

Li L, Weintraub L, Concepcion W, Martin JP, Miller K, Salvatierra O, Sarwal MM

Interference of globin genes with biomarker discovery for allograft rejection in peripheral blood samples.

Physiological genomics

Li L, Ying L, Naesens M, Xiao W, Sigdel T, Hsieh S, Martin J, Chen R, Liu K, Mindrinos M, Davis R, Sarwal M

Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance.

Proceedings of the National Academy of Sciences of the United States of America

Brouard S, Mansfield E, Braud C, Li L, Giral M, Hsieh SC, Baeten D, Zhang M, Ashton-Chess J, Braudeau C, Hsieh F, Dupont A, Pallier A, Moreau A, Louis S, Ruiz C, Salvatierra O, Soulillou JP, Sarwal M

Transplant reno-vascular stenoses associated with early erythropoietin use.

Clinical transplantation

Nagarajan S, Mansfield E, Hsieh S, Liu R, Hsieh F, Li L, Salvatierra O, Sarwal MM

The evolution of nonimmune histological injury and its clinical relevance in adult-sized kidney grafts in pediatric recipients.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Naesens M, Kambham N, Concepcion W, Salvatierra O, Sarwal M

Immunosuppression minimization in pediatric transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Sarwal M, Pascual J

Optimizing outcomes for neonatal ARPKD.

Pediatric transplantation

Beaunoyer M, Snehal M, Li L, Concepcion W, Salvatierra O, Sarwal M

Sirolimus is not always responsible for new-onset proteinuria after conversion for chronic allograft nephropathy.

Pediatric transplantation

Abdurrahman Z, Sarwal M, Millan M, Robertson S, Filler G

Subclinical cytomegalovirus and Epstein-Barr virus viremia are associated with adverse outcomes in pediatric renal transplantation.

Pediatric transplantation

Li L, Chaudhuri A, Weintraub LA, Hsieh F, Shah S, Alexander S, Salvatierra O, Sarwal MM

Proteinuria in pediatric renal transplant recipients during the first 60 post-transplant days.

Pediatric transplantation

Chua AN, Alexander SR, Sarwal MM, Millan M, Salvatierra O, Yorgin PD

Successful renal transplantation in high-risk small children with a completely thrombosed inferior vena cava.

Transplantation

Eneriz-Wiemer M, Sarwal M, Donovan D, Costaglio C, Concepción W, Salvatierra O

A novel, semiquantitative, clinically correlated calcineurin inhibitor toxicity score for renal allograft biopsies.

Clinical journal of the American Society of Nephrology : CJASN

Kambham N, Nagarajan S, Shah S, Li L, Salvatierra O, Sarwal MM

Microarrays: a monitoring tool for transplant patients?

Transplant international : official journal of the European Society for Organ Transplantation

Weintraub LA, Sarwal MM

Option of pre-emptive nephrectomy and renal transplantation for Bartter's syndrome.

Pediatric transplantation

Chaudhuri A, Salvatierra O, Alexander SR, Sarwal MM

Three cases of suspected antibody-mediated rejection.

Clinical transplants

Sutherland SM, Sarwal M

Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling.

Kidney international

Melk A, Mansfield ES, Hsieh SC, Hernandez-Boussard T, Grimm P, Rayner DC, Halloran PF, Sarwal MM

Steroid elimination is coming of age.

Pediatric nephrology (Berlin, Germany)

Sarwal M

Mycophenolate mofetil in pediatric renal transplantation.

Transplantation

Ettenger R, Sarwal MM

Expression profiling of murine double-negative regulatory T cells suggest mechanisms for prolonged cardiac allograft survival.

Journal of immunology (Baltimore, Md. : 1950)

Lee BP, Mansfield E, Hsieh SC, Hernandez-Boussard T, Chen W, Thomson CW, Ford MS, Bosinger SE, Der S, Zhang ZX, Zhang M, Kelvin DJ, Sarwal MM, Zhang L

Corticosteroid avoidance in pediatric renal transplantation.

Pediatric nephrology (Berlin, Germany)

Vidhun JR, Sarwal MM

Gastrointestinal leukocytoclastic vasculitis: an adverse effect of sirolimus.

Pediatric transplantation

Nagarajan S, Friedrich T, Garcia M, Kambham N, Sarwal MM

Vulnerability of small pediatric recipients to laparoscopic living donor kidneys.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Salvatierra O, Sarwal M

First NIH/Office of Rare Diseases Conference on Cystinosis: past, present, and future.

Pediatric nephrology (Berlin, Germany)

Kleta R, Kaskel F, Dohil R, Goodyer P, Guay-Woodford LM, Harms E, Ingelfinger JR, Koch VH, Langman CB, Leonard MB, Mannon RB, Sarwal M, Schneider JA, Skovby F, Sonies BC, Thoene JG, Trauner DA, Gahl WA, NIH Office of Rare Diseases

Management of methylmalonic acidaemia by combined liver-kidney transplantation.

Journal of inherited metabolic disease

Nagarajan S, Enns GM, Millan MT, Winter S, Sarwal MM

Correlation between gene expression and morphological alterations in baboon carotid after balloon dilatation injury.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Aavik E, Mahapatra A, Boldrick J, Chen X, Barry C, Dutoit D, Sarwal M, Häyry P

Arraying the orchestration of allograft pathology.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Mansfield ES, Sarwal MM

Microarrays: interrogating the transplant transcriptosome.

Clinical transplants

Shah S, Sarwal MM

Noncirrhotic portal hypertension in association with juvenile nephropathic cystinosis: case presentation and review of the literature.

Journal of inherited metabolic disease

DiDomenico P, Berry G, Bass D, Fridge J, Sarwal M

Postdialysis albumin: a better nutrition marker in pediatric hemodialysis patients?

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation

Wapensky T, Alexander SR, Sarwal M

A typology of non-adherence in pediatric renal transplant recipients.

Pediatric transplantation

Shaw RJ, Palmer L, Blasey C, Sarwal M

Applications of microarrays to renal transplantation: progress and possibilities.

Frontiers in bioscience : a journal and virtual library

Chua MS, Mansfield E, Sarwal M

Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling.

The New England journal of medicine

Sarwal M, Chua MS, Kambham N, Hsieh SC, Satterwhite T, Masek M, Salvatierra O

Chronic rejection: prospects for therapeutic intervention in fibroproliferative vascular disease.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

Häyry P, Aavik E, Sarwal M, du Toit D, Vamvakopoulos J

Microarrays: new tools for transplantation research.

Pediatric nephrology (Berlin, Germany)

Chua MS, Sarwal MM

Increased expression of cytotoxic effector molecules: different interpretations for steroid-based and steroid-free immunosuppression.

Pediatric transplantation

Satterwhite T, Chua MS, Hsieh SC, Chang S, Scandling J, Salvatierra O, Sarwal MM

Molecular profiling of anemia in acute renal allograft rejection using DNA microarrays.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Chua MS, Barry C, Chen X, Salvatierra O, Sarwal MM

Promising early outcomes with a novel, complete steroid avoidance immunosuppression protocol in pediatric renal transplantation.

Transplantation

Sarwal MM, Yorgin PD, Alexander S, Millan MT, Belson A, Belanger N, Granucci L, Major C, Costaglio C, Sanchez J, Orlandi P, Salvatierra O

Visual loss caused by pseudotumor cerebri in an infant on peritoneal dialysis.

Pediatric nephrology (Berlin, Germany)

Belson A, Alcorn DM, Yorgin PD, Fisher PG, Sarwal M

Genomic analysis of renal allograft dysfunction using cDNA microarrays.

Transplantation proceedings

Sarwal M, Chang S, Barry C, Chen X, Alizadeh A, Salvatierra O, Brown P

Granulysin expression is a marker for acute rejection and steroid resistance in human renal transplantation.

Human immunology

Sarwal MM, Jani A, Chang S, Huie P, Wang Z, Salvatierra O, Clayberger C, Sibley R, Krensky AM, Pavlakis M

Sodium ferric gluconate therapy in renal transplant and renal failure patients.

Pediatric nephrology (Berlin, Germany)

Yorgin PD, Belson A, Sarwal M, Alexander SR

A 100% 2-year graft survival can be attained in high-risk 15-kg or smaller infant recipients of kidney allografts.

Archives of surgery (Chicago, Ill. : 1960)

Millan MT, Sarwal MM, Lemley KV, Yorgin P, Orlandi P, So S, Alexander S, Salvatierra O

Pulmonary capillary leak syndrome with intravenous cyclosporin A in pediatric renal transplantation.

Pediatric transplantation

Mackie FE, Umetsu D, Salvatierra O, Sarwal MM

A new, unique and simple method for ureteral implantation in kidney recipients with small, defunctionalized bladders.

Transplantation

Salvatierra O, Sarwal M, Alexander S, Lemley KV, Yorgin P, Al-Uzri A, Lu A, Millan M, Alfrey E

Transplantation of adult-sized kidneys into infants induces major blood flow changes.

Transplantation proceedings

Salvatierra O, Singh T, Shifrin R, Conley S, Alexander S, Tanney D, Lemley K, Sarwal M, Mackie F, Alfrey E, Orlandi P, Zarins C, Herfkens R

Successful transplantation of adult-sized kidneys into infants requires maintenance of high aortic blood flow.

Transplantation

Salvatierra O, Singh T, Shifrin R, Conley S, Alexander S, Tanney D, Lemley K, Sarwal M, Mackie F, Alfrey E, Orlandi P, Zarins C, Herfkens R