Marlys Fassett, MD, PhD

+1 415 353-7800

Please call UCSF Dermatology at 415 353 7800 for clinical care inquiries or appointments. The telephone number listed here is not monitored.


Neuropeptide substance P alters stem cell fate to aid wound healing and promote epidermal stratification through asymmetric stem cell divisions.

Stem cells (Dayton, Ohio)

Khalifa A, Xiao T, Abegaze B, Weisenberger T, Charruyer A, Sanad S, AbuElnasr T, Kashem SW, Fassett M, Ghadially R

An essential role for miR-15/16 in Treg suppression and restriction of proliferation.

Cell reports

Johansson K, Gagnon JD, Zhou SK, Fassett MS, Schroeder AW, Kageyama R, Bautista RA, Pham H, Woodruff PG, Ansel KM

IL-31-dependent neurogenic inflammation restrains cutaneous type 2 immune response in allergic dermatitis.

Science immunology

Fassett MS, Braz JM, Castellanos CA, Salvatierra JJ, Sadeghi M, Yu X, Schroeder AW, Caston J, Munoz-Sandoval P, Roy S, Lazarevsky S, Mar DJ, Zhou CJ, Shin JS, Basbaum AI, Ansel KM

Evaluation of Gabapentin and Transforaminal Corticosteroid Injections for Brachioradial Pruritus.

JAMA dermatology

Gutierrez RA, Berger TG, Shah V, Agnihothri R, Demir-Deviren S, Fassett MS

Innate type 2 immunity controls hair follicle commensalism by Demodex mites.


Ricardo-Gonzalez RR, Kotas ME, O'Leary CE, Singh K, Damsky W, Liao C, Arouge E, Tenvooren I, Marquez DM, Schroeder AW, Cohen JN, Fassett MS, Lee J, Daniel SG, Bittinger K, Díaz RE, Fraser JS, Ali N, Ansel KM, Spitzer MH, Liang HE, Locksley RM

Obesity alters pathology and treatment response in inflammatory disease.


Bapat SP, Whitty C, Mowery CT, Liang Y, Yoo A, Jiang Z, Peters MC, Zhang LJ, Vogel I, Zhou C, Nguyen VQ, Li Z, Chang C, Zhu WS, Hastie AT, He H, Ren X, Qiu W, Gayer SG, Liu C, Choi EJ, Fassett M, Cohen JN, Sturgill JL, Crotty Alexander LE, Suh JM, Liddle C, Atkins AR, Yu RT, Downes M, Liu S, Nikolajczyk BS, Lee IK, Guttman-Yassky E, Ansel KM, Woodruff PG, Fahy JV, Sheppard D, Gallo RL, Ye CJ, Evans RM, Zheng Y, Marson A

Incidence and Characteristics of Delayed Injection Site Reaction to the mRNA-1273 SARS-CoV2 Vaccine (Moderna) in a Cohort of Hospital Employees.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Jacobson MA, Zakaria A, Maung Z, Hart C, McCalmont T, Fassett M, Amerson E

Varicella Zoster and Herpes Simplex Virus Reactivation Post-COVID-19 Vaccination: A Review of 40 Cases in an International Dermatology Registry.

Journal of the European Academy of Dermatology and Venereology : JEADV

Fathy RA, McMahon DE, Lee C, Chamberlin GC, Rosenbach M, Lipoff JB, Tyagi A, Desai SR, French LE, Lim HW, Thiers BH, Hruza GJ, Fassett M, Fox LP, Greenberg HL, Blumenthal K, Freeman EE

Cold and COVID: recurrent pernio during the COVID-19 pandemic.

The British journal of dermatology

Freeman EE, McMahon DE, Lipoff JB, Rosenbach M, Desai SR, Fassett M, French LE, Lim HW, Hruza GJ, Fox LP

Genetic priming of sensory neurons in mice that overexpress PAR2 enhances allergen responsiveness.

Proceedings of the National Academy of Sciences of the United States of America

Braz JM, Dembo T, Charruyer A, Ghadially R, Fassett MS, Basbaum AI

Long COVID in the skin: a registry analysis of COVID-19 dermatological duration.

The Lancet. Infectious diseases

McMahon DE, Gallman AE, Hruza GJ, Rosenbach M, Lipoff JB, Desai SR, French LE, Lim H, Cyster JG, Fox LP, Fassett MS, Freeman EE

Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation.


Liu Y, Cook C, Sedgewick AJ, Zhang S, Fassett MS, Ricardo-Gonzalez RR, Harirchian P, Kashem SW, Hanakawa S, Leistico JR, North JP, Taylor MA, Zhang W, Man MQ, Charruyer A, Beliakova-Bethell N, Benz SC, Ghadially R, Mauro TM, Kaplan DH, Kabashima K, Choi J, Song JS, Cho RJ, Cheng JB

Timing of PCR and antibody testing in patients with COVID-19-associated dermatologic manifestations.

Journal of the American Academy of Dermatology

Freeman EE, McMahon DE, Hruza GJ, Lipoff JB, French LE, Fox LP, Fassett MS

Treatment of PD-1/PD-L1 Inhibitor-Induced Dermatitis Resolves Concomitant Eruptive Keratoacanthomas.

JAMA dermatology

Crow LD, Perkins I, Twigg AR, Fassett MS, LeBoit PE, Berger TG, Khodosh R

Neuroimmune interactions in chronic itch of atopic dermatitis.

Journal of the European Academy of Dermatology and Venereology : JEADV

Yosipovitch G, Berger T, Fassett MS

miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival.

Cell reports

Gagnon JD, Kageyama R, Shehata HM, Fassett MS, Mar DJ, Wigton EJ, Johansson K, Litterman AJ, Odorizzi P, Simeonov D, Laidlaw BJ, Panduro M, Patel S, Jeker LT, Feeney ME, McManus MT, Marson A, Matloubian M, Sanjabi S, Ansel KM

Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution.

Cell reports

Cheng JB, Sedgewick AJ, Finnegan AI, Harirchian P, Lee J, Kwon S, Fassett MS, Golovato J, Gray M, Ghadially R, Liao W, Perez White BE, Mauro TM, Mully T, Kim EA, Sbitany H, Neuhaus IM, Grekin RC, Yu SS, Gray JW, Purdom E, Paus R, Vaske CJ, Benz SC, Song JS, Cho RJ

Identification of Functionally Relevant microRNAs in the Regulation of Allergic Inflammation.

Methods in molecular biology (Clifton, N.J.)

Fassett MS, Pua HH, Simpson LJ, Steiner DF, Ansel KM

A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells.

Nature immunology

Fu W, Ergun A, Lu T, Hill JA, Haxhinasto S, Fassett MS, Gazit R, Adoro S, Glimcher L, Chan S, Kastner P, Rossi D, Collins JJ, Mathis D, Benoist C

Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion.

Proceedings of the National Academy of Sciences of the United States of America

Fassett MS, Jiang W, D'Alise AM, Mathis D, Benoist C

The Immunological Genome Project: networks of gene expression in immune cells.

Nature immunology

Heng TS, Painter MW, Immunological Genome Project Consortium

Viral evasion of natural killer cells.

Nature immunology

Orange JS, Fassett MS, Koopman LA, Boyson JE, Strominger JL

Signaling at the inhibitory natural killer cell immune synapse regulates lipid raft polarization but not class I MHC clustering.

Proceedings of the National Academy of Sciences of the United States of America

Fassett MS, Davis DM, Valter MM, Cohen GB, Strominger JL

The human natural killer cell immune synapse.

Proceedings of the National Academy of Sciences of the United States of America

Davis DM, Chiu I, Fassett M, Cohen GB, Mandelboim O, Strominger JL