Lisa Singer, MD, PhD

Assistant Professor
Radiation Oncology
+1 415 353-9826

Dr. Singer is an attending physician and Assistant Professor in Radiation Oncology at UCSF, where she specializes in the use of radiation to treat breast cancer, thoracic cancer, and ventricular tachycardia. She also serves as Clinical Magnetic Resonance Imaging (MRI) Director in Radiation Oncology and is board-certified in both radiation oncology and MRI safety. She received a PhD in Bioengineering from the University of California, Berkeley and University of California, San Francisco in 2010, focusing on breast MRI, and then her MD from the University of California, San Francisco in 2012. She completed internship at Lenox Hill Hospital in New York City, residency at University of California, San Francisco and fellowship focusing on women's health at MD Anderson Cancer Center in Houston, Texas. She then worked as an attending physician at Brigham and Women's Hospital, Dana-Farber Cancer Institute and Harvard Medical School for three years where she served as MR Medical Director and Assistant Professor in Radiation Oncology. Dr. Singer has worked on advancing the use of MRI for the care of patients with cancer for over 10 years and continues to develop this technology for the care of patients with breast cancer, lung cancer as well as other cancers.

Her research focuses on the use of imaging to improve our ability to 1) predict tumor response to treatment, and 2) to target tumors with radiotherapy. She has developed and led multiple clinical trials in this space. Prediction of tumor response earlier in a patient’s treatment course could allow for earlier changes in therapy, improving outcomes. Additionally, prediction of normal tissue toxicity at earlier timepoints could inform changes in radiation planning, reducing morbidity. She is also interested in developing novel methods to improve safety and education surrounding biomedical imaging and image-guided radiotherapy.

Together with her colleagues in medical oncology and surgery, she strives to provide exceptional, multidisciplinary care for all of her patients.

Publications: 

Linac- and CyberKnife-based MRI-only treatment planning of prostate SBRT using an optimized synthetic CT calibration curve.

Journal of applied clinical medical physics

Scholey J, Nano T, Singhrao K, Mohammad O, Singer L, Larson PEZ, Descovich M

Management of Concurrent Malignant Phyllodes Tumor and Invasive Breast Carcinoma.

Advances in radiation oncology

Chen JJ, Zhu I, Patel A, Krings G, Chen YY, Yuen F, Mukhtar RA, Melisko M, Singer L, Park CC, Prionas ND

Incidental findings and safety events from magnetic resonance imaging simulation for head and neck radiation treatment planning: A single institution experience.

Technical innovations & patient support in radiation oncology

Massachi J, Singer L, Glastonbury C, Scholey J, Singhrao K, Calvin C, Yom SS, Chan JW

Finding Resonance: Using MRI to Improve the Care of Oligometastatic Disease.

International journal of radiation oncology, biology, physics

Singer L, Scholey J

Little Downside.

International journal of radiation oncology, biology, physics

Singer L, Rugo HS

Transitioning to Environmentally Sustainable, Climate-Smart Radiation Oncology Care.

International journal of radiation oncology, biology, physics

Lichter KE, Anderson J, Sim AJ, Baniel CC, Thiel CL, Chuter R, Collins A, Carollo E, Berg CD, Coleman CN, Abdel-Wahab M, Grover S, Singer L, Mohamad O

Environmentally sustainable brachytherapy care.

Brachytherapy

Lichter KE, Baniel CC, Anderson J, Bhatia R, Frick MA, Thiel CL, Gandhi S, Sarria GR, Bagshaw HP, Petereit D, Chino J, Grover S, Singer L, Hsu IC, Mohamad O

Regional Nodal Management After Preoperative Systemic Therapy.

Seminars in radiation oncology

Singer L, Weiss A, Bellon JR, King TA

Education in gynecological brachytherapy.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Fields EC, Kahn JM, Singer L

Geographic differences in therapy for stage I non-small-cell lung cancer in older adults.

Journal of surgical oncology

Dezube AR, Mazzola E, Cooper L, Deeb AL, De-Leon LE, Singer L, Jacobson FL, Jaklitsch MT, Wiener D

Clinical outcomes and dosimetric predictors of toxicity for re-irradiation of vaginal recurrence of endometrial cancer.

Brachytherapy

Lee LJ, Alban GM, Cheng T, Buzurovic I, Pretz J, Singer L, King MT

Surgical complications and clinical outcomes after dose-escalated trimodality therapy for non-small cell lung cancer in the era of intensity-modulated radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Liu KX, Sierra-Davidson K, Tyan K, Orlina LT, Marcoux JP, Kann BH, Kozono DE, Mak RH, White A, Singer L

Actualizing Risk-Adapted Thoracic Stereotactic Body Radiation Therapy with MR Guidance

Applied Radiation Oncology

Singer L, Kann BH, Cagney DN, Leeman JE, Yom SS, Kozono D

Rates of invasive disease and outcomes in NSCLC patients with biopsy suggestive of carcinoma in situ.

Lung cancer (Amsterdam, Netherlands)

Talcott WJ, Miccio JA, Park HS, White AA, Kozono DE, Singer L, Sands JM, Sholl LM, Detterbeck FC, Mak RH, Decker RH, Kann BH

Definitive radiotherapy for vaginal recurrence of early-stage endometrial cancer: survival outcomes and effect of mismatch repair status.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Alban G, Cheng T, Adleman J, Buzurovic I, Pretz J, Singer L, King M, Lee L

Development and Implementation of an Online Adaptive Stereotactic Body Radiation Therapy Workflow for Treatment of Intracardiac Metastasis.

Practical radiation oncology

Shi DD, Liu KX, Hacker F, Hanna GJ, Kwong RY, Cagney DN, Mak RH, Singer L

Use of a healthy volunteer imaging program to optimize clinical implementation of stereotactic MR-guided adaptive radiotherapy.

Technical innovations & patient support in radiation oncology

Boyle PJ, Huynh E, Boyle S, Campbell J, Penney J, Usta I, Neubauer Sugar E, Hacker F, Williams C, Cagney D, Mak R, Singer L

50 Gray is Not Enough.

International journal of radiation oncology, biology, physics

Singer L, Lee LJ

Simulation-based graduate medical education in MR-guided brachytherapy for cervical cancer.

Brachytherapy

Singer L, McLaughlin PY, Alban G, Joyner M, King M, Lee L

A new development in ultrasound-compatible gynecologic brachytherapy simulators.

Brachytherapy

Fields EC, Joyner MM, Singer L, Todor D

IJROBP

Impact of Healthy Volunteer MR-Linac Imaging on Clinical Implementation of Stereotactic MR-Guided Online Adaptive Radiotherapy

Boyle PJ, Huynh E, Sugar EN, Hacker FL, Boyle S, Usta I, Campbell J, Penney J, Bernal A, Williams CL, Cagney DN, Mak RH, Singer L

IJROBP

STAMPing out MRI Simulation Hazards with a System-Theoretic Accident Model and Processes Approach to Proactive Hazard Assessment

Wong L, Huynh E, Mak RH, Leveson N, Singer L

MRI in Radiation Oncology After the COVID-19 Pandemic.

International journal of radiation oncology, biology, physics

Singer L, Marques A, Cagney DN, Kaza E

Clinical Characteristics Associated With Stuttering Persistence: A Meta-Analysis.

Journal of speech, language, and hearing research : JSLHR

Singer CM, Hessling A, Kelly EM, Singer L, Jones RM

A review of the role of MRI in diagnosis and treatment of early stage lung cancer.

Clinical and translational radiation oncology

Sim AJ, Kaza E, Singer L, Rosenberg SA

Master Protocol Trial Design for Efficient and Rational Evaluation of Novel Therapeutic Oncology Devices.

Journal of the National Cancer Institute

Bitterman DS, Cagney DN, Singer LL, Nguyen PL, Catalano PJ, Mak RH

Low-Dose Adjuvant Cylinder Brachytherapy for Endometrioid Endometrial Cancer.

Practical radiation oncology

Alban GM, Buscariollo DL, Cheng T, Pretz J, Krechmer B, Buzurovic I, Singer L, King M, Lee L

Development of a Multi-Institutional Simulation-Based Gynecologic Brachytherapy Curriculum.

International journal of radiation oncology, biology, physics

Singer L, Damast S, Lin L, Taunk N, Lee LJ, Albuquerque K, Chino J, Petereit D, Joyner M, Fields E

Pocket Radiation Oncology

Esophageal Cancer

Singer L, Brooke E, Gomez D

Quality Improvement Initiative to Improve Tobacco Cessation Efforts in Radiation Oncology.

Journal of oncology practice

Singer L, Sharee K, Boreta L, Silveira WR, Braunstein S, Fogh S

Palliative radiotherapy near the end of life.

BMC palliative care

Wu SY, Singer L, Boreta L, Garcia MA, Fogh SE, Braunstein SE

The Impact of MRI on Radiation Oncology Graduate Medical Education.

Journal of the American College of Radiology : JACR

Singer L, Rosenberg SA

Toxicities of Radiation Treatment for Breast Cancer

Considerations for Post-Mastectomy Radiation Therapy in the Setting of Breast Reconstruction

Singer L, Wright J

Residents' Views on Tobacco Cessation in Radiation Oncology.

Journal of the American College of Radiology : JACR

Singer L, Braunstein S, Singer CM, Silveira WR, Fogh S

Handbook of Evidence-Based Radiation Oncology

Cutaneous lymphomas

Singer L, Garsa A

Features of MRI stromal enhancement with neoadjuvant chemotherapy: a subgroup analysis of the ACRIN 6657/I-SPY TRIAL.

Journal of medical imaging (Bellingham, Wash.)

Olshen A, Wolf D, Jones EF, Newitt D, van ‘t Veer LJ, Yau C, Esserman L, Wulfkuhle JD, Gallagher RI, Singer L, Petricoin EF, Hylton N, Park CC

Journal of Clinical Oncology

Factors associated with palliative radiotherapy in the last 30 days of life

Wu S, Singer L, Garcia MA, Fogh SE, Braunstein SE

IJROBP

Dynamic contrast-enhanced MRI in monitoring changes in tumor-associated stroma during treatment with neoadjuvant chemotherapy in patients with locally advanced breast cancer

Singer L, Jones E, Newitt D, Kornak J, Hylton N, Park CC

IJROBP

Radiation within 30 Days of death: TEACHH score and ability to complete treatment

Wu S, Singer L, Xu C, Gjyshi O, Fogh S, Braunstein S

Journal of Clinical Oncology

Role of emergent palliative radiation therapy in the care of patients with cancer

Singer L, Zhang M, Braunstein S, Fogh S

IJROBP

A quality improvement study to improve assessment of patient readiness to quit tobacco prior to treatment with radiation therapy

Singer L, Boreta L, Braunstein S, Fogh S

Slant board immobilisation of head-and-neck radiotherapy patients who cannot tolerate a flat position

Journal of Radiotherapy in Practice

Qu S., Singer L., Chen J., Shugard E., Garsa A., Yom S.

Xanthogranuloma in the heavily irradiated low neck in a patient with head and neck cancer.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale

Singer L, Calkins SM, Horvai AE, Ryan WR, Yom SS

Looking Ahead: Practicing Radiation Oncology in the Era of ICD-10.

International journal of radiation oncology, biology, physics

Singer L, Braunstein S, Fogh SE

IJROBP

Quality improvement study on reducing time from new patient evaluation for bone metastasis to time of CT simulation

Singer L, Chang J, Johnson J, Polishchuk A, Choi S, Fogh S

Consolidative radiation therapy for extensive-stage small cell lung cancer.

Translational lung cancer research

Singer L, Yom SS

IJROBP

Tobacco cessation perspectives and practice among U.S. radiation oncology residents

Braunstein S, Singer L, Silveira W, Fogh SE

High-resolution diffusion-weighted imaging for monitoring breast cancer treatment response.

Academic radiology

Wilmes LJ, McLaughlin RL, Newitt DC, Singer L, Sinha SP, Proctor E, Wisner DJ, Saritas EU, Kornak J, Shankaranarayanan A, Banerjee S, Jones EF, Joe BN, Hylton NM

2012 ISMRM Annual Meeting Proceedings

High-resolution DWI for characterizing breast tumor response to treatment

Wilmes LJ, McLaughlin RL, Sinha S, Newitt DC, Singer L, Proctor E, Wisner D, Saritas EU, Shankaranarayanan A, Banerjee S, Joe BN, Hylton NM

High-resolution diffusion-weighted magnetic resonance imaging in patients with locally advanced breast cancer.

Academic radiology

Singer L, Wilmes LJ, Saritas EU, Shankaranarayanan A, Proctor E, Wisner DJ, Chang B, Joe BN, Nishimura DG, Hylton NM

Cancer Research

Improved Spatial Resolution Diffusion-Weighted Imaging for Characterizing Tumors and Treatment Response in Patients with Invasive Breast Cancer

LJ Wilmes, R McLaughlin, S Sinha, L Singer, E Proctor, D Wisner, DN Newitt, A Shankaranarayanan, BN Joe and NM Hylton

Quantification of background enhancement in breast magnetic resonance imaging.

Journal of magnetic resonance imaging : JMRI

Klifa C, Suzuki S, Aliu S, Singer L, Wilmes L, Newitt D, Joe B, Hylton N

International Society for Magnetic Resonance in Medicine 19th Annual Meeting & Exhibition

Reduced field-of-view diffusion-weighted imaging in patients with invasive breast cancer

Singer L, Wilmes LJ, Saritas EU, Shankaranarayanan A, Proctor E, Wisner D, Chang B, Joe BN, Nishimura DG, Hylton NM

Diffusion-Weighted Magnetic Resonance Imaging in Monitoring Treatment Response in Patients with Locally Advanced Breast Cancer

Diffusion-Weighted Magnetic Resonance Imaging in Monitoring Treatment Response in Patients with Locally Advanced Breast Cancer

Singer L

International Workshop on Breast Densitometry and Breast Cancer Risk Assessment

Towards a "one-click" method of volumetric breast density calculation from magnetic resonance imaging data

Singer L, Hylton N, Klifa C

Role of IV iodinated contrast material in 18F-FDG PET/CT of liver metastases.

AJR. American journal of roentgenology

Badiee S, Franc BL, Webb EM, Chu B, Hawkins RA, Coakley F, Singer L

Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans.

Organic & biomolecular chemistry

Zezula J, Singer L, Przybyl AK, Hashimoto A, Dersch CM, Rothman RB, Deschamps J, Lee YS, Jacobson AE, Rice KC

Abstract Archives of the RSNA

Non-enhanced CT versus standard dose contrast-enhanced CT in combined PET/CT protocols for assessing metastatic liver lesions

Badiee, S, Coakley, F, Franc, B, Ruppert, A, Webb, E, Hawkins, R, Singer L, Schreck, C

Flying ions in disguise: the effects of esterification on fragmentation patterns of proteolytic digests in electrospray ionization tandem mass spectrometry

Flying ions in disguise: the effects of esterification on fragmentation patterns of proteolytic digests in electrospray ionization tandem mass spectrometry

Singer L