Ruyan Rahnama, MD, MSc, PhD

Adjunct Instructor
Pediatrics
[email protected]

Instructor in Pediatric Oncology with clinical and research focus in childhood leukemia and the development of novel engineered cell therapies using natural killer cells as an effector platform.

Publications: 

Single-chain variable fragment affinity tuning can optimize anti-AML CAR-NK cell functionality.

Journal for immunotherapy of cancer

Rahnama R, Kizerwetter M, Yang H, Christodoulou I, Guaraca C, Holl NJ, Choe J, Vorri SC, Zinsky M, Jones DG, Garcia Espinoza N, Kuo YH, Zahurak M, Varadhan R, Spangler JB, Bonifant CL

Brain Metastasis in Pediatric Patients with Osteosarcoma.

Current oncology (Toronto, Ont.)

Murphy J, Sundby RT, Resch EE, Rahnama R, Lemberg KM, Maalouf A, Suru A, Fixler J, Ladle BH, Rhee DS, Levin AS, Pallavajjala A, Gocke C, Ladra MM, Groves ML, Acharya S, Gross JM, Llosa NJ, Pratilas CA

Activation of Cell-Intrinsic Signaling in CAR-T Cells via a Chimeric IL7R Domain.

Cancer research communications

Vorri SC, Holl NJ, Leeming M, Apostolova P, Marple A, Ravich JW, Canbaz A, Rahnama R, Choe J, Modi A, Fearnow AD, Walsh STR, Pearce EL, Varadhan R, Bonifant CL

Engineering builds multipotency for iPSC-NKs.

Blood

Rahnama R, Bonifant CL

Gene-Based Natural Killer Cell Therapies for the Treatment of Pediatric Hematologic Malignancies.

Hematology/oncology clinics of North America

Rahnama R, Christodoulou I, Bonifant CL

Glycoprotein Targeted CAR-NK Cells for the Treatment of SARS-CoV-2 Infection.

Frontiers in immunology

Christodoulou I, Rahnama R, Ravich JW, Seo J, Zolov SN, Marple AN, Markovitz DM, Bonifant CL

Engineering CAR-NK cells to secrete IL-15 sustains their anti-AML functionality but is associated with systemic toxicities.

Journal for immunotherapy of cancer

Christodoulou I, Ho WJ, Marple A, Ravich JW, Tam A, Rahnama R, Fearnow A, Rietberg C, Yanik S, Solomou EE, Varadhan R, Koldobskiy MA, Bonifant CL

Access to harm reduction programs among persons who inject drugs: findings from a respondent-driven sampling survey in Tehran, Iran.

The International journal on drug policy

Rahnama R, Mohraz M, Mirzazadeh A, Rutherford G, McFarland W, Akbari G, Malekinejad M

Trophic stimulation of articular chondrocytes by late-passage mesenchymal stem cells in coculture.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Wang M, Rahnama R, Cheng T, Grotkopp E, Jacobs L, Limburg S, Kim HT, Kuo AC

Cytotoxicity of local anesthetics on human mesenchymal stem cells.

The Journal of bone and joint surgery. American volume

Rahnama R, Wang M, Dang AC, Kim HT, Kuo AC

Comparison of gene expression patterns in articular cartilage and dedifferentiated articular chondrocytes.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Cheng T, Maddox NC, Wong AW, Rahnama R, Kuo AC