PROF IN RES-HCOMP
M_Dermatology
+1 415 750-2091 ext. 3371
Publications
Epidermal Penetration Increases with Age and May Contribute to Systemic Inflammation.
The Journal of investigative dermatology
Sphingosine-1-phosphate-cathelicidin axis plays a pivotal role in the development of cutaneous squamous cell carcinoma.
The Journal of investigative dermatology
Restoring Endoplasmic Reticulum Calcium Stores in Aged Epidermis Improves the Epidermal Calcium Gradient and Enhances Filaggrin Expression.
The Journal of investigative dermatology
Link between the skin and autism spectrum disorder.
Frontiers in psychiatry
Association of Epidermal Biophysical Properties with Obesity and its Implications.
Skin pharmacology and physiology
Sodium in the Skin: A summary of the physiology and scoping review of disease associations.
Clinical and experimental dermatology
Link between obesity and atopic dermatitis: Does obesity predispose to atopic dermatitis, or vice versa?
Experimental dermatology
Skin Barrier Function and Cognition Among Older Adults.
The Journal of investigative dermatology
FLG Deficiency in Mice Alters the Early-Life CD4+ T-Cell Response to Skin Commensal Bacteria.
The Journal of investigative dermatology
Skin and bone crosstalk during aging.
Nature aging
ALOX12B and PNPLA1 Have Distinct Roles in Epidermal Lipid Lamellar Organization.
The Journal of investigative dermatology
Alterations in epidermal function in type 2 diabetes: Implications for the management of this disease.
Journal of diabetes
The link between cutaneous inflammation and cognitive impairment.
Journal of the European Academy of Dermatology and Venereology : JEADV
Classification of human chronic inflammatory skin disease based on single-cell immune profiling.
Science immunology
Epidermal Basement Membrane Substitutes for Bioengineering of Human Epidermal Equivalents.
JID innovations : skin science from molecules to population health
Role of nitric oxide in regulating epidermal permeability barrier function.
Experimental dermatology
Ode to Salt: Commentary on "Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity".
The Journal of investigative dermatology
Decreased Calcium-Sensing Receptor Expression Controls Calcium Signaling and Cell-To-Cell Adhesion Defects in Aged Skin.
The Journal of investigative dermatology
Unbound Corneocyte Lipid Envelopes in 12R-Lipoxygenase Deficiency Support a Specific Role in Lipid-Protein Cross-Linking.
The American journal of pathology
CERKL is upregulated in cutaneous squamous cell carcinoma and maintains cellular sphingolipids and resistance to oxidative stress.
The British journal of dermatology
Mutations in 3�-hydroxysteroid-d8, d7-isomerase paradoxically benefit epidermal permeability barrier homeostasis in mice.
Experimental dermatology
Markers for Ca++ -induced terminal differentiation of keratinocytes in vitro under defined conditions.
Experimental dermatology
Inducible nitric oxide synthase is required for epidermal permeability barrier homeostasis in mice.
Experimental dermatology
Perspective and Consensus Opinion: Good Practices for Using Organotypic Skin and Epidermal Equivalents in Experimental Dermatology Research.
The Journal of investigative dermatology
Ischemic Fasciitis Mimicking A Lipoma.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
Botulinum toxin type A suppresses pro-fibrotic effects via the JNK signaling pathway in hypertrophic scar fibroblasts.
Archives of dermatological research
Induced pluripotent stem cell line heterozygous for p.R501X mutation in filaggrin: KCLi003-A.
Stem cell research
The pathological role of Wnt5a in psoriasis and psoriatic arthritis.
Journal of cellular and molecular medicine
Induced pluripotent stem cell line heterozygous for p.R2447X mutation in filaggrin: KCLi002-A.
Stem cell research
Topical applications of an emollient reduce circulating pro-inflammatory cytokine levels in chronically aged humans: a pilot clinical study.
Journal of the European Academy of Dermatology and Venereology : JEADV
A20 and ABIN1 Suppression of a Keratinocyte Inflammatory Program with a Shared Single-Cell Expression Signature in Diverse Human Rashes.
The Journal of investigative dermatology
Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte�Lipid Envelope.
The Journal of investigative dermatology
Calcium-Sensing Receptor Regulates Epidermal�Intracellular Ca2+ Signaling and Re-Epithelialization after Wounding.
The Journal of investigative dermatology
Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution.
Cell reports
A data mining paradigm for identifying key factors in biological processes using gene expression data.
Scientific reports
Circulating zearalenone and its metabolites differ in women due to body mass index and food intake.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Mohs Micrographic Surgery in the Veterans Health Administration.
Federal practitioner : for the health care professionals of the VA, DoD, and PHS
Warfarin-Associated Nonuremic Calciphylaxis.
JAMA dermatology
Epidermal Dysfunction Leads to an Age-Associated Increase in Levels of Serum�Inflammatory Cytokines.
The Journal of investigative dermatology
Voriconazole exposure regulates distinct cell-cycle and terminal differentiation pathways in primary human keratinocytes.
The British journal of dermatology
Induced Pluripotent Stem Cell Differentiation and Three-Dimensional Tissue Formation Attenuate Clonal Epigenetic Differences in Trichohyalin.
Stem cells and development
Endoplasmic Reticulum Calcium Regulates Epidermal Barrier Response and Desmosomal Structure.
The Journal of investigative dermatology
Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production.
Journal of dermatological science
Altered epidermal lipid processing and calcium distribution in the KID syndrome mouse model Cx26S17F.
FEBS letters
UVB induces epidermal 11�-hydroxysteroid dehydrogenase type 1 activity in vivo.
Experimental dermatology
Sebaceous gland, hair shaft, and epidermal barrier abnormalities in keratosis pilaris with and without filaggrin deficiency.
The American journal of pathology
Lowered humidity produces human epidermal equivalents with enhanced barrier properties.
Tissue engineering. Part C, Methods
Topical hesperidin enhances epidermal function in an aged murine model.
The Journal of investigative dermatology
Topical hesperidin prevents glucocorticoid-induced abnormalities in epidermal barrier function in murine skin.
Experimental dermatology
Endoplasmic reticulum calcium, stress, and cell-to-cell adhesion.
The Journal of investigative dermatology
Ibrutinib rash in a patient with 17p del chronic lymphocytic leukemia.
American journal of hematology
Calcium, Orai1, and epidermal proliferation.
The Journal of investigative dermatology
3D In vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells.
Stem cell reports
Basis for enhanced barrier function of pigmented skin.
The Journal of investigative dermatology
Increased glucocorticoid activation during mouse skin wound healing.
The Journal of endocrinology
Comparison of publication trends in dermatology among Japan, South Korea and Mainland China.
BMC dermatology
sPLA2 and the epidermal barrier.
Biochimica et biophysica acta
Ten-year publication trends in dermatology in mainland China.
International journal of dermatology
Local blockade of glucocorticoid activation reverses stress- and glucocorticoid-induced delays in cutaneous wound healing.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Topical apigenin improves epidermal permeability barrier homoeostasis in normal murine skin by divergent mechanisms.
Experimental dermatology
Systemic retinoids in the management of ichthyoses and related skin types.
Dermatologic therapy
Topical apigenin alleviates cutaneous inflammation in murine models.
Evidence-based complementary and alternative medicine : eCAM
Tight junction properties change during epidermis development.
Experimental dermatology
SERCA2-controlled Ca�+-dependent keratinocyte adhesion and differentiation is mediated via the sphingolipid pathway: a therapeutic target for Darier's disease.
The Journal of investigative dermatology
Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.
Proceedings of the National Academy of Sciences of the United States of America
Regulation of cathelicidin antimicrobial peptide expression by an endoplasmic reticulum (ER) stress signaling, vitamin D receptor-independent pathway.
The Journal of biological chemistry
Temporal dissection of tumorigenesis in primary cancers.
Cancer discovery
Acidification in the epidermis and the role of secretory phospholipases.
Dermato-endocrinology
A topical Chinese herbal mixture improves epidermal permeability barrier function in normal murine skin.
Experimental dermatology
Major translocation of calcium upon epidermal barrier insult: imaging and quantification via FLIM/Fourier vector analysis.
Archives of dermatological research
Endoplasmic reticulum Ca2+ depletion activates XBP1 and controls terminal differentiation in keratinocytes and epidermis.
The British journal of dermatology
Is the filaggrin-histidine-urocanic acid pathway essential for stratum corneum acidification?
The Journal of investigative dermatology
The epidermal Ca(2+) gradient: Measurement using the phasor representation of fluorescent lifetime imaging.
Biophysical journal
Epidermal barrier dysfunction in non-atopic HIV: evidence for an "inside-to-outside" pathogenesis.
The Journal of investigative dermatology
Murine atopic dermatitis responds to peroxisome proliferator-activated receptors alpha and beta/delta (but not gamma) and liver X receptor activators.
The Journal of allergy and clinical immunology
Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes.
The Journal of investigative dermatology
Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens.
The Journal of allergy and clinical immunology
Akt2 and SGK3 are both determinants of postnatal hair follicle development.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis.
The Journal of investigative dermatology
pH-regulated mechanisms account for pigment-type differences in epidermal barrier function.
The Journal of investigative dermatology
Topical peroxisome proliferator activated receptor activators accelerate postnatal stratum corneum acidification.
The Journal of investigative dermatology
Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2.
The American journal of pathology
Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice.
The Journal of clinical investigation
Stratum corneum acidification is impaired in moderately aged human and murine skin.
The Journal of investigative dermatology
Focal adhesion kinase controls pH-dependent epidermal barrier homeostasis by regulating actin-directed Na+/H+ exchanger 1 plasma membrane localization.
The American journal of pathology
CaR talk: the calcium receptor finds new places to park.
The Journal of investigative dermatology
Involucrin expression is decreased in Hailey-Hailey keratinocytes owing to increased involucrin mRNA degradation.
The Journal of investigative dermatology
Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Glucocorticoid blockade reverses psychological stress-induced abnormalities in epidermal structure and function.
American journal of physiology. Regulatory, integrative and comparative physiology
Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome.
The Journal of investigative dermatology
Topical treatment with thiazolidinediones, activators of peroxisome proliferator-activated receptor-gamma, normalizes epidermal homeostasis in a murine hyperproliferative disease model.
Experimental dermatology
Activity of the hSPCA1 Golgi Ca2+ pump is essential for Ca2+-mediated Ca2+ response and cell viability in Darier disease.
Journal of cell science
Extracellular pH Controls NHE1 expression in epidermis and keratinocytes: implications for barrier repair.
The Journal of investigative dermatology
Sarcoidosis associated with pegylated interferon alfa and ribavirin treatment for chronic hepatitis C: a case report and review of the literature.
Archives of dermatology
Development of multiple lipomas during treatment with rosiglitazone in a patient with HIV-associated lipoatrophy.
AIDS (London, England)
Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development.
Molecular biology of the cell
Functional consequences of a neutral pH in neonatal rat stratum corneum.
The Journal of investigative dermatology
Analysis: blood glucose monitoring: making the possible practical.
Diabetes technology & therapeutics
Stratum corneum acidification in neonatal skin: secretory phospholipase A2 and the sodium/hydrogen antiporter-1 acidify neonatal rat stratum corneum.
The Journal of investigative dermatology
Actin reorganization is abnormal and cellular ATP is decreased in Hailey-Hailey keratinocytes.
The Journal of investigative dermatology
Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores.
The Journal of investigative dermatology
'The discovery channel': CRAC'king the code of calcium influx.
The Journal of investigative dermatology
Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function.
The Journal of investigative dermatology
Defective cyclic guanosine monophosphate-gated calcium channels and the pathogenesis of psoriasis.
Acta dermato-venereologica
NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging.
The Journal of biological chemistry
Two-photon fluorescence lifetime imaging of the skin stratum corneum pH gradient.
Biophysical journal
Epidermal expression of the full-length extracellular calcium-sensing receptor is required for normal keratinocyte differentiation.
Journal of cellular physiology
The ENaC channel is required for normal epidermal differentiation.
The Journal of investigative dermatology
Treatment of an ulcerated hemangioma with recombinant platelet-derived growth factor.
Archives of dermatology
Changes in HOXB6 homeodomain protein structure and localization during human epidermal development and differentiation.
Developmental dynamics : an official publication of the American Association of Anatomists
The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation.
The Journal of biological chemistry
Epithelial sodium channels are upregulated during epidermal differentiation.
The Journal of investigative dermatology
Using lasers in diabetic wound healing.
Diabetes technology & therapeutics
Acute barrier perturbation abolishes the Ca2+ and K+ gradients in murine epidermis: quantitative measurement using PIXE.
The Journal of investigative dermatology
The secretory granular cell: the outermost granular cell as a specialized secretory cell.
The journal of investigative dermatology. Symposium proceedings
Barrier recovery is impeded at neutral pH, independent of ionic effects: implications for extracellular lipid processing.
Archives of dermatological research
Formation of the epidermal calcium gradient coincides with key milestones of barrier ontogenesis in the rodent.
The Journal of investigative dermatology
Keratinocyte K+ channels mediate Ca2+-induced differentiation.
The Journal of investigative dermatology
Calcium and potassium inhibit barrier recovery after disruption, independent of the type of insult in hairless mice.
Experimental dermatology
Activation of keratinocyte nicotinic cholinergic receptors stimulates calcium influx and enhances cell differentiation.
The Journal of investigative dermatology
Changes in calcium responsiveness and handling during keratinocyte differentiation. Potential role of the calcium receptor.
The Journal of clinical investigation
Disseminated cutaneous Cryptococcus clinically mimicking basal cell carcinoma.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
Treatment of leg ulcers with cultured epithelial autografts: clinical study and case reports.
Ostomy/wound management
Amiloride blocks a keratinocyte nonspecific cation channel and inhibits Ca(++)-induced keratinocyte differentiation.
The Journal of investigative dermatology
Treatment of pyoderma gangrenosum with cultured keratinocyte autografts.
The Journal of dermatologic surgery and oncology
A role for ions in barrier recovery after acute perturbation.
The Journal of investigative dermatology
Mal de Meleda in a Laotian family.
International journal of dermatology
Ion channels are linked to differentiation in keratinocytes.
The Journal of membrane biology
Acrodermatitis enteropathica in a patient with the acquired immunodeficiency syndrome.
Archives of dermatology
Autologous skin grafts for leg ulcers.
The Western journal of medicine
Urticaria and hepatitis C.
Lancet (London, England)
Extracellular calcium affects the membrane currents of cultured human keratinocytes.
Journal of cellular physiology
Establishment of a human cutaneous T-cell lymphoma in C.B-17 SCID mice.
The Journal of investigative dermatology
Linear granuloma annulare.
Journal of the American Academy of Dermatology
Effects of TPA on short-circuit current across frog skin.
The American journal of physiology
Effects of tumor promoters on sodium ion transport across frog skin.
The American journal of physiology
Postcapillary pH disequilibrium after gas exchange in isolated perfused liver.
Journal of applied physiology: respiratory, environmental and exercise physiology