Noa Simchoni, MD, PhD | Women Physician-Scientists @UCSF

Activated STING in the thymic epithelium alters T cell development and selection leading to autoimmunity.

The Journal of clinical investigation

Deng Z, Law CS, Kurra S, Simchoni N, Shum AK

Functional Validation of Variants of Unknown Significance in COPA Syndrome.

American journal of respiratory and critical care medicine

N. Simchoni, S. Agezew, A. Shum

The common HAQ STING allele prevents clinical penetrance of COPA syndrome.

The Journal of experimental medicine

Simchoni N, Koide S, Likhite M, Kuchitsu Y, Kadirvel S, Law CS, Elicker BM, Kurra S, Wong MM, Yuan B, Grossi A, Laxer RM, Volpi S, Dissanayake D, Taguchi T, Beck DB, Vogel TP, Shum AK

Activated STING in the thymus alters T cell development and selection leading to autoimmunity.

bioRxiv : the preprint server for biology

Deng Z, Law CS, Kurra S, Simchoni N, Shum AK

Pathogenic COPA mutations decrease binding of dilysine motifs through allosteric effects.

Biophysical journal

Anna Pavlova, Sasthi C. Mandal, Noa Simchoni, Christopher S. Law, Atanu Acharya, Anthony K. Shum, James C. Gumbart

COPA Syndrome from Diagnosis to Treatment: A Clinician's Guide.

Rheumatic diseases clinics of North America

Simchoni N, Vogel TP, Shum AK

Implementation of Clinical Practice Guidelines for Hospitalized Patients With COVID-19 in Academic Medical Centers.

JAMA network open

Berger AC, Simchoni N, Auerbach A, Brode WM, Kuperman E, Raffel K, Kubey A, HOMERuN COVID-19 Collaborative Group

AN UNUSUAL CASE OF INNUMERABLE LUNG NODULES.

CHEST Journal

Noa Simchoni, Lurit Bepo, Kaitlyn Tracy, Travis Zack

Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses.

The Journal of experimental medicine

Ruane D, Chorny A, Lee H, Faith J, Pandey G, Shan M, Simchoni N, Rahman A, Garg A, Weinstein EG, Oropallo M, Gaylord M, Ungaro R, Cunningham-Rundles C, Alexandropoulos K, Mucida D, Merad M, Cerutti A, Mehandru S

Expansion of inflammatory innate lymphoid cells in patients with common variable immune deficiency.

The Journal of allergy and clinical immunology

Cols M, Rahman A, Maglione PJ, Garcia-Carmona Y, Simchoni N, Ko HM, Radigan L, Cerutti A, Blankenship D, Pascual V, Cunningham-Rundles C

High-throughput sequencing reveals an altered T cell repertoire in X-linked agammaglobulinemia.

Clinical immunology (Orlando, Fla.)

Ramesh M, Simchoni N, Hamm D, Cunningham-Rundles C

IgH sequences in common variable immune deficiency reveal altered B cell development and selection.

Science translational medicine

Roskin KM, Simchoni N, Liu Y, Lee JY, Seo K, Hoh RA, Pham T, Park JH, Furman D, Dekker CL, Davis MM, James JA, Nadeau KC, Cunningham-Rundles C, Boyd SD

Toll-like receptor signaling in primary immune deficiencies.

Annals of the New York Academy of Sciences

Maglione PJ, Simchoni N, Cunningham-Rundles C

Biliary Epithelial Cells Are Not the Predominant Source of Hepatic CXCL12.

The American journal of pathology

Saiman Y, Sugiyama T, Simchoni N, Spirli C, Bansal MB

TLR7- and TLR9-responsive human B cells share phenotypic and genetic characteristics.

Journal of immunology (Baltimore, Md. : 1950)

Simchoni N, Cunningham-Rundles C

Clonal and constricted T cell repertoire in Common Variable Immune Deficiency.

Clinical immunology (Orlando, Fla.)

Ramesh M, Hamm D, Simchoni N, Cunningham-Rundles C

IRAK-4 and MyD88 deficiencies impair IgM responses against T-independent bacterial antigens.

Blood

Maglione PJ, Simchoni N, Black S, Radigan L, Overbey JR, Bagiella E, Bussel JB, Bossuyt X, Casanova JL, Meyts I, Cerutti A, Picard C, Cunningham-Rundles C

Selectivity of Toll-like receptor stimulation in human B cells (HUM8P.350).

The Journal of Immunology

Noa Simchoni, Charlotte Cunningam-Rundles

Deep sequencing of the IgH locus in CVID reveals global alterations in central and peripheral B cell development (P3329).

The Journal of Immunology

Noa Simchoni, Krishna Roskin, Scott Boyd, Charlotte Cunningam-Rundles

Publications