HS Assoc Clinical Professor
M_MED-CORE-PULM
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I am a Pulmonary and Critical Care Physician-Scientist. My clinical and research specialties are in Cystic Fibrosis lung infection and inflammation. I am the Principal Investigator of a basic science laboratory, and I serve as the Associate Program director of the UCSF Adult Cystic Fibrosis Center. I attend regularly in the ICUs at Parnassus and Mount Zion and am passionate about improving medical education particularly during COVID when our learners have faced unforeseen challenges.
Publications
Investigating Pseudomonas aeruginosa Gene Function During Pathogenesis Using Mobile-CRISPRi.
Methods in molecular biology (Clifton, N.J.)
Codelivery of synergistic antimicrobials with polyelectrolyte nanocomplexes to treat bacterial biofilms and lung infections.
Science advances
Human Fetal Tissue Regulation. Impact on Pediatric and Adult Respiratory-related Research.
Annals of the American Thoracic Society
Antibiotic adverse reactions in adult cystic fibrosis patients.
The journal of allergy and clinical immunology. In practice
Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation.
The Journal of clinical investigation
Sensing Living Bacteria in Vivo Using d-Alanine-Derived 11C Radiotracers.
ACS central science
Modulating Pathogenesis with Mobile-CRISPRi.
Journal of bacteriology
Two tyrosyl radicals stabilize high oxidation states in cytochrome C oxidase for efficient energy conservation and proton translocation.
Journal of the American Chemical Society
Radical formation in cytochrome c oxidase.
Biochimica et biophysica acta
Differential effects of glutamate-286 mutations in the aa(3)-type cytochrome c oxidase from Rhodobacter sphaeroides and the cytochrome bo(3) ubiquinol oxidase from Escherichia coli.
Biochimica et biophysica acta
EPR characterization of ascorbyl and sulfur dioxide anion radicals trapped during the reaction of bovine Cytochrome c Oxidase with molecular oxygen.
Journal of magnetic resonance (San Diego, Calif. : 1997)