Claire Clelland, MD, PhD

Asst Professor Clin Neurology
M_Neurology
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Dr. Clelland, PhD, MD, MPhil, is an Assistant Professor in the UCSF Department of Neurology. As a neurologist, she specializes in caring for patients with dementia and cognitive symptoms at the UCSF Memory & Aging Center. Her lab at the UCSF Weill Institute for Neurosciences develops novel therapies for neurodegenerative diseases. Her current work centers on creating novel CRISPR gene therapies for genetic forms of neurodegenerative diseases such as frontotemporal dementia (FTD), Alzheimer's disease (AD), Parkinson's disease (PD) and amytrophic lateral sclerosis (ALS). Her lab utilizes patient iPSCs to model disease, advanced sequencing technologies and cutting-edge CRISPR technologies to develop first-in-class gene therapies for CNS diseases. The Clelland lab is committed to promoting equity and justice in science in medicine. One of the pillars of the Clelland lab is the mentoring and advancement of trainees from underrepresented backgrounds to become the next generation of scientific leaders.

Publications

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Frost B, Rowe JB, Akinyemi RO, Abisambra JF, Ashton NJ, Brendel M, Buée L, Butler D, Carrillo MC, Chung P, Clelland CD, DeVos SL, Diaz K, Edelmayer RM, Elahi FM, Ellajosyula R, Ewen C, Fontana IC, Galas MC, Hansson O, Höglinger G, Horie K, Ibanez A, Jacobs L, Maina MB, Malpetti M, McDade E, McEwan W, Montoliu-Gaya L, Mummery CJ, Orr ME, Rohrer JD, Rommel A, Sastre C, Spires-Jones TL, Tee BL, Viney TJ, Walker JM, Wegmann S, Wildsmith K, Yadav R, Mahinrad S, Sexton C

Novel avenues of tau research.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MB, Clelland CD, Cohen AD, Crary JF, Dage JL, Diaz K, Frost B, Gan L, Goate AM, Golbe LI, Hansson O, Karch CM, Kolb HC, La Joie R, Lee SE, Matallana D, Miller BL, Onyike CU, Quiroz YT, Rexach JE, Rohrer JD, Rommel A, Sadri-Vakili G, Schindler SE, Schneider JA, Sperling RA, Teunissen CE, Weninger SC, Worley SL, Zheng H, Carrillo MC